Forschung am BBZ  

Forschung am BBZ

Ausgewählte Wissenschaftliche Veröffentlichungen 2015

Eschke M, Piehler D, Schulze B, Richter T, Grahnert A, Protschka M, Müller U, Köhler G, Höfling C, Rossner S, Alber G
A novel experimental model of Cryptococcus neoformans-related immune reconstitution inflammatory syndrome (IRIS) provides insights into path-ogenesis. Eur J Immunol. (2015) Dec; 45(12):3339-50

Arendt T, Brückner MK, Lösche A
Regional mosaic genomic heterogeneity in the elderly and in Alzheimers disease as a correlate of neuronal vulnerability. Acta Neuropathol (2015); 130(4): 501-510, ISSN 0001-6322

Giri S, Bader A

A low-cost, high-quality new drug discovery process using patient-derived induced pluripotent stem cells. Drug Discov Today (2015); 20(1): 37-49, ISSN 2544-8756

Baums CG, von Köckritz-Blickwede M
Novel role of DNA in neutrophil extracellular traps. Trends Microbiol. (2015) Jun;23(6):330-1

Ahrens V, Kostelnik K, Rennert R, Böhme D, von Bergen M, Weber L, Beck-Sickinger AG
A cleavable cytolysin-NPY-conjugate enables specific drug delivery while retaining cytoxic mode of action,  J Contr Release (2015), 209, 170-178

Thürmann S, Lotter C, Heiland JJ, Chankvetadze B, Belder D.
Chip-Based High-Performance Liquid Chromatography for High-Speed Enantioseparations. Anal. Chem. (2015), 87, 5568–5576

Elumalai N, Berg A, Natarajan K, Scharow A, Berg T.
Nanomolar inhibitors of the transcription factor STAT5b with high selectivity over STAT5a. Angew. Chem. Int. Ed. 2015; 54, 4758-4763; Angew. Chem. (2015), 127, 4840–4845

Sabri O, Becker  GA, Meyer PM, Hesse S, Wilke S, Graef S., Patt M, Luthardt J, Wagenknecht G, Hoepping A, Smits R, Franke A, Sattler B, Habermann B, Neuhaus P, Fischer S, Tiepolt S, Deuther-Conrad W, Barthel H, Schönknecht P, Brust P.

First-in-human PET quantification study of cerebral α4β2* nicotinic acetylcholine receptors using the novel specific radioligand (-)-[18F]Flubatine. Neuroimage 118 (2015), 199-208

Russ A, Reitemeier S, Weissmann A, Gottschalk J, Einspanier A, Klenke R.
Seasonal and urban effects on the endocrinology of a wild passerine. Ecology and Evolution (2015), DOI:10.1002/ece3.1820

Fischer M, Quaas M, Steiner L, Engeland K.
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes. Nucleic Acids Res (2015), ISSN

Vemula V, Ni Z, Fedorova M
Fluorescence labeling of carbonylated lipids and proteins in cells using coumarin-hydrazide. Redox Biology. 23(5), (2015), 195-204

Ulbricht D, Pippel J, Schultz S, Meier R, Sträter N, Heiker JT

A Unique Serpin P1‘ Glutamate and a Conserved ß-Sheet C Arginine are Key Residues for Activity, Protease Recognition and Stability of SerpinA12 (Vaspin). Biochemical Journal, 470 (3), (2015), 357-367

Neumann P, Dib H, Caminade AM, Hey-Hawkins E

Redox Control of a Dendritic Homogeneous Catalyst. Angew. Chem. Int. Ed. 54 (2015) 311-314; Angew. Chem. 127 (2015), 316-319

Krizsan A, Knappe D, Hoffmann R
Influence of yjiL and upstream genes on the antibacterial activity of proline-rich antimicrobial peptides overcoming Escherichia coli resistance induced by the missing SbmA transporter system. Antimicrob. Agents Chemother (2015). 59(10): 5992-8. PMID: 26169420

Heine P, Ehrlicher A, Käs JA
Neuronal and metastatic cancer cells: Unlike brothers, Bio-chim. Biophys. Acta (BBA) - Molecular Cell Research (2015), 1853, Issue 11, 3126-3131

Homberg M, Ramms L, Schwarz N, Dreissen G, Leube RE, Merkel R, Hoffmann B, Magin TM
Distinct impact of two keratin mutations causing epidermolysis bullosa simplex on keratinocyte adhesion and stiffness.  J Invest Dermatol (2015), 135: 2437-2445

Sapudom J, Rubner S, Marin S, Kurth T, Riedel S, Mierke CT, Pompe T
The phenotype of cancer cell invasion controlled by fibril diameter and pore size of 3D collagen networks. Biomaterials (2015), Volume 52, pp. 376-375, doi:10.1016/j.biomaterials.2015.02.022

Wende S, Götze O, Betat H, Mörl M
The Discriminator Position is important for CCA-Addition. Nucleic Acids Res. (2015), 43, No. 11, 5617-5629

Sapudom J, Rubner S, Martin S, Thoenes S, Anderegg U, Pompe T
The interplay of fibronectin functionalization and TGF-beta1 presence on fibroblast proliferation, differentiation and migration in 3D matrices. Biomater Sci. (2015);3: 1291-1301

Hartung M, Groß A, Kirsten T, Rahm E
Effective Composition of Mappings for Matching Biomedical Ontologies. The Semantic Web: ESWC 2012 Satellite Events, Springer-Verlag Berlin Heidelberg 2015, LNCS 7540 (2015), pp. 176–190

Eichler M, Jahnke HG, Krinke D, Müller A, Schmidt S, Azendorf R, Robitzki AA
A novel 96-well- multielectrode array based impedimetric monitoring platform for comparative drug efficacy analysis on 2D and 3D brain tumor cultures. Biosens Bioelectron. (2015), 67: 582-589

Oesterling P, Jähnichen P, Heyer G, Scheuermann G
Topological visual analysis of clusterings in high-dimensional information spaces. it - Information Technology, (2015), Volume 57, p.3-10

Schöneberg T, Liebscher I, Luo R, Monk KR, Piao X
Tethered agonists: a new mechanism underlying adhesion G protein-coupled receptor activation. J Recept Signal Transduct R. 2015;35 (2015), 220-3

Zscharnack M, Krause C, Aust G, Thümmler C, Peinemann F, Keller T, Smink JJ, Holland H, Somerson JS, Knauer J, Schulz RM, Lehmann J

Preclinical Good Laboratory Practice-Compliant Safety Study to Evaluate Biodistribution and Tumorigenicity of a Cartilage Ad-vanced Therapy Medicinal Product (ATMP). Journal of Translational Medicine (2015), 13: 160

Roßteuscher-Carl K, Fricke S, Hacker MC, Schulz-Siegmund  M
Influence of in line monitored fluid bed granulation process parameters on the stability of Ethinylestradiol, Int J Pharm. 2015 Dec 30;496(2) (2015), 751-8

Schubert S, Heller S, Loffler B, Schafer I, Seibel M, Villani G, Seibel P
Generation of Rho Zero Cells: Visualization and Quantification of the mtDNA Depletion Process. Int J Mol Sci (2015); 16 (5): 9850-9865

Treudler R, Reuter A, Engin AM, Simon JC
A Case of Anaphylaxis After Garlic Ingestion: Is Alliinase the Only Culprit Allergen? J Investig Allergol Clin Immunol (2015); 25(5): 73-74

Stadler PF
Evolution of RNA-Based Networks. Quasispecies: From Theory to Experimental Systems. Curr Top Microbiol Immunol. 392 (2015), 43-59

Kloos  M, Brüser A, Kirchberger  J,  Schöneberg T, Sträter N
Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem. J. (2015) 469, 421-432

Wilhelm C, Wirth C.
Physiodiversity - New tools allow physiologist to embrace biodiversity and reconstruct the evolution of 'physiologies'? J. Plant Phyisol. (2015), 172, 1-3

Allenstein U, Mayr SG, Zink M
Contractile cell forces deform macroscopic cantilevers and quantify biomaterial performance, Soft Matter, (2015), Volume 11, Issue 25, 5053-5059

letzte Änderung: 02.02.2017