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Research Report
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Faculty of Veterinary Medicine |
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Research Activities at the Faculty
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Reports of the Institutes and Departments
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Research Activities at the Faculty
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The projects of the veterinary faculty are focused on the following topics
1. Products of animal origin and consumer protection
2. Preventive veterinary medicine
3. Clinical veterinary medicine
4. Ecological animal husbandry
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Postgraduate Research Unit "Influence of
Stress on Animals for Slaughtering and Safety of Animal Products"
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As far as consumer protection is concerned, various
departments are involved in the postgraduate research unit "Influence of
Stress on Animals for
Slaughtering and Safety of Animal Products".
In 1999, the postgraduate research unit projects enjoyed its second period of
funding. The projects are as follows:
- Influence of stressors on the mechanisms of detoxification and compensation
(Institute of Bacteriology and Mycology)
- Influence of stressors on the clinical manifestation of persistent salmonella
infections - characterisation of the mechanisms leading to infection (Institute of
Animal Hygiene and Public Veterinary Science)
- Effect of endotoxin treatment on the course on an asymptomatic persisting
salmonella infection (Institute of Immunology)
- Detoxification by the gut (Institute of Veterinary Physiology)
- Influence of stressors on the translocation of viruses and on the reactivation of
inapparent infections (Institute of Virology)
- Ethological investigations on the behaviour of stressed and unstressed animals
(Ethology team, Institute of Food Hygiene)
- Characterisation of antibacterial quality of pork and its alterations by premortal
stressors (Institute of Food Hygiene)
- Functional morphology of gastrointestinal barrier of pigs and its reaction against
antigens (Institute of Veterinary Pathology)
- Translocation of antigens at biological cell barriers - in vitro investigations
(Institute of Veterinary Pathology)
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Consumer Protection
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In addition to the postgraduate research unit, various groups are working on the
problems of "Consumer Protection", dealing with various
infections and trying
to establish diagnostic systems for assuring the quality of meat, milk and eggs:
- Serological and molecular biological characterisation of pork and food
contaminated by salmonella and Yersinia infections (Institute of Animal Hygiene and
Public Veterinary Science)
- Combating salmonella in pork production of Saxony (Institute of Food
Hygiene)
- Model for the prediction of food spoilage (Institute of Food Hygiene in
co-operation with the School of Health and Sports Science (University of North
London) and with Sezione di Chimica e Tecnologia degli Alimenti (University of
Bologna))
- Development of in-vitro-models for the investigation of harmlessness of food
from animal origin (Institute of Pharmacology, Pharmacy and Toxicology)
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Preventive Veterinary Medicine
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Within "preventive veterinary medicine", various drugs
and food additives are tested and vaccines are developed. Furthermore, an attempt is
made to
characterise immunological and adaptive responses of animals:
- Development of Yersinia vaccines based on recombinant factors of virulence
(Institute of Animal Hygiene and Public Veterinary Science)
- Decontamination of animal waste by composting (Institute of Animal Hygiene and
Public Veterinary Science)
- Role of fatty acids and antioxidants in prophylaxis and therapy of diseases of
domestic animals (Institute of Veterinary Physiological Chemistry)
- Immunostimulatory activity of the p40 subunit of interleukin-12 (Institute of
Immunology in co-operation with the Centre for Veterinary Science (University of
Cambridge, UK), the Institute of Pathology of the Albert Ludwig University, Freiburg,
the Borstel Research Centre, the Virological Institute of the University
of Zurich, and the University of Cape Town (South Africa))
- Treatment of ecto- and endoparasites with Selamectin (Institute of
Parasitology)
- Adaptation of transport processes in the ruminant forestomach (Institute of
Veterinary Physiology in co-operation with the Institute of Veterinary Physiology
of the Hanover College of Veterinary Medicine, the Physiology Centre at the University
of Göttingen, the Forskningcenter Foulom (Tjele, Danmark), and the
University of Hisar (India))
- Preventive food additives (Institute of Animal Nutrition, Nutritional Disturbances
and Dietetics)
- Pathomorphology and pathophysiology of degeneration in the retina induced by
Borna disease viruses (BDV) (Institute of Veterinary Anatomy in co-operation
with various institutes of the University of Leipzig and the Institute of Virology,
Department of Veterinary Medicine, of the University of Giessen)
- Developing and testing modern vaccination strategies for novel approaches to
fight against infectious diseases of horses (Institute of Virology in collaboration
with the University of Heidelberg, the DKFZ (German Cancer Research Centre) in
Heidelberg, and industrial partners)
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Clinical Veterinary Medicine
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Within "clinical veterinary medicine", an attempt is being
made to transfer diagnostic procedures established in human medicine to the specific
demands of
veterinary medicine. Furthermore, pathogenic mechanisms of certain animal diseases
are elucidated and therapy plans are developed. In detail, the following
projects are worked on:
- Investigations into imaging systems to be used in the diagnosis of CNS diseases
and of acquired deformities (Small Domestic Animals Clinic)
- Serological and molecular biological diagnosis of the bovine protothecosis
(Institute of Animal Hygiene and Public Veterinary Science)
- Controlling and optimisation of reproduction in domestic animals (Large Animal
Clinic for Theriogenology and Ambulatory Services)
- Minimal invasive surgery and anaesthesiology (Surgical Animal Clinic in
co-operation with the University of Saskatchewan (Canada))
- Growth of dogs with regard to their nutrition and skeletal diseases (Institute of
Veterinary Anatomy)
- Pathology, aetiology, pathogenesis, diagnosis and prognosis of genital diseases
in male and female horses (Institute of Veterinary Pathology in co-operation
with the Hanover College of Veterinary Medicine, the University of Potsdam, the Lower
Saxony Stud Farm, Celle, the Cambridge University/ Newmarket
(UK), the University of Zurich (Switzerland) and the University of Porto Alegre
(Brasil))
- Liver diseases of dogs and cats: pathology, aetiology, pathogenesis, diagnosis
and prognosis (Institute of Veterinary Pathology in co-operation with the
Hanover College of Veterinary Medicine)
- Pathogenesis of chronic caecal obstipations and of gastric ulcers in horses
(Large Animal Medicine Clinic)
- High-yield cows: maintenance of health in the peripartal period (Large Animal
Medicine Clinic in co-operation with the University of Utrecht and the
Hanover College of Veterinary Medicine)
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Ecological Animal Husbandry
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Within "ecological animal husbandry", the Faculty is
investigating the legal requirement for veterinarians to deal with the consequences of
animal husbandry.
Work is being conducted on the following projects:
- Non-chemical fly control (Institute of Parasitology)
- Reduction of N-excretion of piglets and pigs (Institute of Animal Nutrition,
Nutritional Disturbances and Dietetics)
In addition to the topics surrounding veterinary medicine, studies are also being
conducted which have an impact on human medicine. For example, the
Veterinary Anatomical Institute is collaborating with the IZKF (Interdisciplinary Centre
for Clinical Research) on the modification of glia-neuron-interaction in
the mammalian retina and on the interrelationship between hypoxy and the
neovascularisation of the retina.
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Research Report 1999 |
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