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Faculty of Chemistry and Mineralogy

Research Activities at the Faculty

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Research Activities at the Faculty

The Faculty of Chemistry and Mineralogy can look back on a successful year of research in 2007, when it shaped many of the research activities at the University of Leipzig. The institutes work on the following complex research programmes:

Graduate School: “Leipzig School of Natural Sciences – Building with Molecules and Nano-objects (BuildMoNa)”
Co-ordinator: Prof. Dr. Evamarie Hey-Hawkins (Institute of Inorganic Chemistry)
The Graduate School “Leipzig School of Natural Sciences – Building with Molecules and Nano-objects (BuildMoNa)” focuses on interdisciplinary graduate education through top-level, synergistic research. Our materials research concept is based on a “bottom-up” approach. Progressive building blocks, such as nano-objects, smart molecules, polymeric scaffolds, peptides, and active proteins, will be combined – preferentially by self-organization – to create fundamentally new classes of materials that are inspired by active, adaptive living matter, and that are environmentally friendly, highly efficient, low-cost devices serving multifunctional purposes for a steadily more diversified modern society. The paradigm shift from uniform bulk materials towards nanostructured multifunctional materials that emerge from combinations of smart molecules, proteins, and nano-objects is essential for the future knowledge transfer from fundamental to applied sciences.

Period: 01.11.2007 - 30.10.2012

Graduate College: “Mechanistic and Applicational Aspects of Non-Conventional Oxidation Reactions”
Co-ordinator: Prof. Dr. Evamarie Hey-Hawkins (Institute of Inorganic Chemistry)
Non-conventional aspects of a central chemical reaction, the oxidation reaction, is studied within an interdisciplinary research programme. In addition to the regular research work within the framework of the doctoral programmes, a special interdisciplinary training programme is available for participating postgraduate students. The main targets of the research programme of the Graduate College are the development of new oxidising agents, their application in synthesis, enzymatic oxidation reactions, including the characterisation and structure determination of the enzymes, and investigation of reactive oxygen species in living organisms.

Period: 01.10.1997 - 30.09.2007

International Postgraduate Programme (IPP): “Research at the Frontiers of Chemistry”
Co-ordinator: Prof. Dr. Evamarie Hey-Hawkins (Institute of Inorganic Chemistry)
This title delineates the international doctorate course of study at the University of Leipzig, at the Faculty of Chemistry and Mineralogy. The doctorate studies, being an International Postgraduate Programme (IPP), are cofinanced by the German Academic Exchange Service (DAAD) and the German Research Council (DFG). The major objectives of the doctorate programme are making the programme more attractive to doctorate students, shortening of the period of doctorate studies and most importantly, internationalising the doctorate programme. All institutes of the Faculty of Chemistry and Mineralogy, as well as the Biotechnological Biomedical Centre, the Institute of Biochemistry and non-academic research establishments take part in the doctorate programme. The scientific profile of the programme is mainly focused on Chemistry-Life Science, Materials Science and Interfaces. However, basic research and environmental topics are additional options.

Period: 01.07.2002 - 30.06.2007

DAAD programme: “Stability Pact for South Eastern Europe” (SOE): “Materials Science and Catalysis Network (MatCatNet)”
Co-ordinator: Prof. Dr. Evamarie Hey-Hawkins (Institute of Inorganic Chemistry)
The aim of the DAAD project is to contribute to the qualification of master and doctoral students in the main chemistry areas Materials Science and Catalysis. The project involves three partner institutions: the Faculty of Chemistry and Mineralogy of the Universität Leipzig, the Faculty of Natural Sciences and Mathematics of the Sts. Cyril and Methodius University (Skopje, Macedonia) and the Faculty of Chemistry and Chemical Engineering of the “Babeş-Bolyai” University (Cluj-Napoca, Romania). The emphasis is on developing high quality courses which and on internationalisation of the study programmes. Common scientific skills, abilities and competences in the field of chemistry will assure the mutual exchange and completion of the Master and doctoral studies. Among the project activities, a major role plays the exchange of students on the Master and doctoral level, of professors and researchers within the network, as well as organisation of intensive courses and workshops.

Period: 01.01.2005 - 31.12.2008

International Study and Training Partnership (ISAP) with Monash University, Clayton, Australia
Co-ordinator: Prof. Dr. Evamarie Hey-Hawkins (Institute of Inorganic Chemistry)
Since 2006, DAAD funds student and lecturer exchanges within the frame of the cooperation between the Faculty of Chemistry and Mineralogy of the Universität Leipzig and the Faculty of Science of the Monash University in Clayton (Victoria, Australia). The ISAP scholarships are meant in particular for chemistry master students beginning with the 2nd semester of study. The content of the training programme is selected according to the major scientific areas of the two faculties. These areas and the credit point transfer regulations are agreed on by both partner institutions. Three scholarships for students and travel grants for 2-3 lecturers are awarded every year.

Period: 01.01.2006 - 31.12.2009

TEMPUS Joint European Project: “Reforms and Upgrade Chemistry Undergraduate Studies in Macedonia”
Co-ordinator: Prof. Dr. Evamarie Hey-Hawkins (Institute of Inorganic Chemistry)
The objective of the TEMPUS JEP project is to contribute to the implementation of the principles of the Bologna declaration through curricula development for undergraduate studies in chemistry sciences at the Faculties of Sciences of the St. Cyril and Methodius University, Skopje, and Tetovo University in Macedonia. This project is funded for two years by the European Commission. The project consortium includes the Faculty of Chemistry and Mineralogy of the Universität Leipzig and the Faculty of Chemistry and Chemical Engineering of the “Babeş-Bolyai” University, Cluj-Napoca, Romania, as European partners. The project curricula will satisfy the needs of Macedonia and at the same time will be compatible with the necessary requirements of common European educational space. The specific project objectives are accredita-tion and implementation of new synchronised BSc curricula and syllabi at Macedonian institutions according to Eurobachelor quality, modernisation of the laboratories for undergraduate practical courses, development and publishing of teaching material, training and exchange of academic and administrative staff and students.

Period: 01.09.2007 - 31.08.2009

International Research Training Group, DFG (1056): “Diffusion in Porous Materials”
Speaker: Prof. Dr. Jörg Kärger (University of Leipzig), Prof. Dr. Freek Kapteijn (Technische Universiteit Delft)

Dissertationsproject: “Isomerization of arylalkanes in porous solid acids. Diffusion and reaction”
Prof. Dr. H. Papp, Dipl.-Chem. M. Löffler, Dipl.-Ing. P. Poladli (University of Leip-zig, Institute of Chemical Technology

Subproject: “Diffusion in ordered mesoporous materials in the vicinity of the pore critical point: Applications in adsorption and heterogeneous catalysis”
Prof. Dr. R Gläser, Prof. Dr. W.-D. Einicke, Dr. K. Böhme (University of Leipzig, Institute of Chemical Technology)

Period: 2004 – 2008

Collaborative Research Center, DFG (706): “Catalytic Selective Oxidations of C-H Bonds Using Molecular Oxygen”
Speaker: Prof. Dr. S. Laschat (University Stuttgart)

Subproject: “Novel Octahedral Redox Molecular Sieves for the Heterogeneously Catalyzed Selective Oxidation of Cyclohexane”
Prof. Dr. R Gläser (Institute of Chemical Technology), Dipl.-Chem. S. Jank (University Stuttgart, Institute of Chemical Technology)
Period: 2006 – 2009

Collaborative Research Center, DFG (624): “Template – From the design of chemical templates to the control of reactions”
Coordinator: Prof. Dr. Karl Heinz Dötz (Kekulé-Institut of Organic Chemistry and Biochemistry, University of Bonn)

Project: “Template effects in solvents and under constraints”
Prof. Dr. B. Kirchner (Wilhelm-Ostwald-Institute of Physical and Theoretical Chemistry, Chair of Theoretical Chemistry), Dr. W. Reckien (University of Bonn, Institute of Physical and Theoretical chemistry), S. Lehmann (Wilhelm-Ostwald-Institute of Physical and Theoretical Chemistry)

This theoretical chemistry project aims at methodological developments as well as at applications in template chemistry. A new aspect of this project is the explicit reatment of the nuclei dynamics. One of the major topics is the investigation of solvent effects on template reactions, because in template reactions hydrogen bonding can play a crucial role. The treatment of template chemistry within the framework of molecular dynamics simulations seems to be appropriate because of the large number of degrees of free-dom in those systems, which is, for instance, reflected in the complexity of these condensed phase systems as in solvents, on surfaces or in crystalline structures as well as in oversized molecules such as catenans, rotaxanes, knots or host-guest receptors. We want to understand how well neoteric solvents like water or ionic liquids can serve as template in analogy to solids that are also used as templates. Furthermore, it is interesting to know how these kinds of reaction can be tuned by the right choice of solvent. Since the time scale of reactions are most often slower than the time scale available in molecular dynamics simulations, constraints that force the reaction will be introduced. The constraint simulations are a branch of molecular dynamics simulations and they are another major topic of this project. Constraints in template reactions will have to consider the increase of entropy. Therefore methods that involve order parameters will be tested. In particular we studied the systems of area B.

Period: 2005-2009

DFG Priority Programme 1191: “Ionic Liquids”
Head: Prof. Dr. P. Wasserscheidt (University of Erlangen-Nürnberg, Chair of Chemical Reaction Engineering)

Project: „Investigations of Ionic Liquid – Solute Systems by surface sensitive spectroscopic techniques“
Prof. Dr. H. Morgner, Dr. G. Andersson (Wilhelm Ostwald Institute of Physical and Theoretical Chemistry)
Period: 01.11.2006 - 30.10.2008

DFG Priority Programme 1191: “Ionic Liquids”
Head: Prof. Dr. P. Wasserscheidt (University of Erlangen-Nürnberg, Chair of Chemical Reaction Engineering)

Project: “Theoretical investigation of intermolecular forces in ionic liquids: Dynamics structure of ionic liquids and interaction with other chemicals with re-spect to reaction and solvent properties”
Prof. Dr. B. Kirchner (Wilhelm-Ostwald-Institute of Physical and Theoretical Chemistry, Chair of Theoretical Chemistry)
If we aim to understand order, dynamics and structure of ionic liquids, part of our work package is to systematically study intermolecular forces with the help of electronic structure calculations. Thereby a relation between the microscopic properties and the macroscopic behavior should be established. Molecular dynamics simulations aid in receiving insight into the degree of ordering, cluster formation and the dynamical behavior of ionic liquids. Interactions of ionic liquids with dissolved substances are studied with the help of first principle simulations. The Car-Parrinello ansatz allows us to observe reactions like proton transfer. Furthermore, model reactions carried out in a molecular-mechanics(MM)-solvent and ion pairs dissolved in molecular liquids are within the scope of this proposal. Thereby structure-forming effects on molecular liquids and the interplay between the different components can be investigated. New structures will be built according to the rationale of the knowledge gained from investigated systems by simple substitution at the side chains and of ions. Analyzing the calculated properties of these new structures will enable us to predict their behavior as solvents in comparison to well-known ionic liquids.

Period: 2005-2008

DFG-Grant-group: “Architecture of nano- and microdimensional building blocks”
Head: Prof. Dr. M. Grundmann (Fakulty of Physics and Geosciences)
Project P4: “Microstructural transformation of lamellar to cylindric cylindrites and its structure-property relations”
Researcher: Prof. Dr. K. Bente (Institute of Mineralogy, Criystallography and Materials Science) with PD Dr. Wagner

Period: since 01.10.2003

DFG Interdisciplinary Research Project: “Interfaces on Oxides”
Co-ordinator: Prof. Dr. I. Mertig (University of Halle-Wittenberg)
Sub-project: X-ray emission spectroscopy of transition metal oxide layers using synchrotron radiation
Researchers: Prof. Dr. R. Szargan, D. Wett, A. Demund (Wilhelm Ostwald Insti-tute of Physical and Theoretical Chemistry)
The aim of the project is to investigate the local electronic structure of epitaxially grown ultrathin multilayers of 3d metal oxides at the interfaces between metals and metal oxides in buried layer structures: charge transfer phenomena, d-d excitation channels, and gap parameters.

Period of funding: July 2000 – December 2007

INNOWATT: “Cleaning of Hydrogen using nanoporous materials for industrial application”
PD Dr.-Ing. R. Staudt (Institute of Non-classical Chemistry)
The aim of this project is to develop a technical process based on adsorption for cleaning of Hydrogen. Different new materials like activated carbon or zeolites will be investigated for hydrogen cleaning by adsorption. Also a theoretical description and simulations of the process will be done.

start 01.01.2007

BMBF-joint Research Project: “Chromatin Modulation: A new approach to therapy of breast cancer”
Co-ordinator: Dr. Miriam Rittner (SiChem GmbH)
Prof. Dr. A. Giannis (Institute of Organic Chemistry)

Period: 01.01.2005 – 31.12.2007

Marie Curie Actions: “Understanding the Dynamics of Cell Division”
Koordinator: Dr. Th. Surrey (EMBL Heidelberg)
Prof. Dr. A. Giannis (Institute of Organic Chemistry)

Period: 01.01.2005 – 31.12.2008

Marie Curie Actions: “Understanding the Dynamics of Cell Division”
Koordinator: Prof. Dr. Th. Mayer (University of Constance)
Prof. Dr. A. Giannis (Institute of Organic Chemistry)

Period: 01.01.2005 – 31.12.2008

Research projects with grants of the DLR and ISTC concerning solar cells in cooperation with Belarus (Academy of Science, Minsk)
Institute of Mineralogy, Crystallography and Materials Science

Period: since 2001

Leipzig-Halle-Jena Research Collaboration
Cooperation and complementarity in research and methodological equipment in the field of mineralogy in higher education
Institute of Mineralogy, Crystallography and Materials Science

Publications, Dissertations and Conferences

The research findings achieved in 2007 were published in scientific journals (see list of scientific publications), summarised in theses (32 doctoral theses and 1 habilitation; see list of dissertations), and presented at congresses, symposia and colloquia. For more detailed information, see the 2007 Annual Report of the Faculty of Chemistry and Mineralogy.

Research Priorities

Institute for Analytical Chemistry

Working group Belder

  • Development and application of microfluidic Lab-On-a-Chip devices with methods: Chip-Electrophoresis,Fluorescence Detection, Mass Spectrometry coupling, Microfluidic reactors, Surface chemistry and coatings
  • New materials and micro patterning techniques: Soft lithography, Bio-Catalysis, Free flow electrophoresis
  • Method and instrument development in capillary electrophoresis: capillary coatings, CE/MS coupling, fluorescence detection

Working group Berger

  • Methodological development and application of Nuclear Magnetic Resonance
  • Development of new pulse sequences including selective pulses for the structural elucidation in organic chemistry
  • Mechanistic investigations in the field of physical organic chemistry
  • Peptide and Protein structure and protein ligand interaction with NMR methods (Collaboration with research framework SFB-610)
  • NMR methods for the investigation of solute solvent interactions. Solvation and Diffusion of organic molecules

Working group Birkemeyer

  • Research analyses in cooperation with users of the mass-spectrometry service
  • Method development on hyphenated techniques with mass spectrometry: Development of an analytical method for multi- selective identification and relative quantification of low-molecular-weight metabolites in biological matrices using different techniques in mass spectrometry

Working group Matysik

  • Methodical developments and applications in the field of capillary elec-trophoresis with electrochemical detection with emphasis on the use of nonaqueous media
  • Development of new approaches for sample injection into microfluidic systems / high-throughput analysis systems
  • Studies of phase optimized liquid chromatography (POPLC)
  • Applied studies in the fields of speciation analysis, electroplating processes, analysis of explosives and related compounds

Institute of Inorganic Chemistry

Solid State Chemistry/Material Sciences
group Prof. Dr. H. Krautscheid

  • Preparation of polynuclear halogeno, pseudohalogeno and chalcogeno complexes – compounds between mononuclear complex and solid state phase
  • Complexes of the heavier main group elements
  • Molecular chalcogenides as precursors for Cu-In chalcogenides and re-lated materials
  • Synthesis and investigation of porous coordination polymers (Metal Or-ganic Frameworks, MOFs)
  • Characterization by X-ray diffraction and spectroscopic methods

Semiconductor Chemistry
group Dr. V. Gottschalch

  • The semiconductor chemistry group focuses on epitaxy of AIIIBV- and AIIBVI-semiconductors. The principal focus of our research is metal organic vapour phase epitaxy (MOVPE) of semiconductors, plasma-enhanced chemical vapour deposition (PECVD) of dielectric layers, structural char-acterisation of epitaxial materials and construction of solar cells, detectors and lasers.
  • The current research activities are focused on the growth phenomena at miniaturisation limits (growth of monolayer, superlattices and self-ordered structures).
  • The main current research interest concerns the growth of nanostructures (nanowires) with various axial and radial heterojunctions based on GaAs-, InAs- and GaN-single crystalline materials and the growth behaviour of nanostructures using various precursors. The growth mechanisms of the vapour liquid solid growth, the selective area growth and the template induced growth were studied.

Organometallic Chemistry/Photochemistry
group Prof. Dr. E. Hey-Hawkins

  • Inorganic Chemistry, Bioorganometallic Chemistry, Organometallic Chem-istry: Synthesis, reactivity and structural elucidation (IR, VV-Vis, NMR, X-ray crystallography) of organometallic, coordination and main group element compounds; reactions of transition metal complexes with functionalized ligands of group 13 and 15 elements; Alkali and Earth Alkaline phospha-nides; Boron compounds; Biologically active carbaboranes for BNCT; Aluminum compounds; (Chiral) phosphorus compounds; Heteronuclear complexes; Homogeneous catalysis; Preparative HPLC for air-sensitive compounds, spectroscopic methods (IR, VV-Vis, NMR) and X-ray crystallography.

Structural Chemistry
group Prof. Dr. R. Kirmse

  • Synhesis, structural characterization and EPR, ENDOR/ESEEM spectroscopic investigations on paramagnetic Cu(II), Ag(II), Au(II), Re(II), Tc(II), Re(VI), Tc(VI), VO(II), Co(II) and Fe(III) complexes with O and S(e) containing chelate ligands and mixed coordination spheres including halides, pseudo-halides and phosphanes. Analysis of the bonding properties and the spin-density distribution in combination with molecular orbital calculations.
  • Synthesis, structural characterization of paramagnetic “molecular squares” of different size and analysis of the EPR/ENDOR spectra in order to draw conclusions about spin exchange between the paramagnetic centers. Synthesis and characterization of microporous, especially para-magnetic metal ions containing two- and three-dimensional networks (MOFs); testing of their applicability with respect to gas adsorp-tion/desorption and catalysis.

Coordination Chemistry
group Prof. Dr. B. Kersting

  • Coordination Chemistry
  • Supramolecular Chemistry/Nanochemistry
  • Molecular Magnetism
  • Bioinorganic Chemistry

Prof. Dr. Dr. h. c. L. Beyer

  • Synthesis and characterization of sulphur containing ligands and their metal complexes
  • History of Chemistry; Chemistry and Art

Institute of Mineralogy, Crystallography and Materials Science

Mineralogy/Crystallography
Prof. Dr. K. Bente

  • Synthesis and “structure (microstructure) – property” relations of mineral – analog semiconductors
  • Interdisciplinary studies using the 3D – X – ray tomography
  • Mathematical simulations of solid state segregations in metal sulfides and of the evalution of the small cylinders in mixed semiconductors.
  • In-situ Mößbauer spectroscopy of the transformation of Fe containing mineral phases

Powder Diffraction
PD Dr. W. Schmitz

  • Synthesis and characterization (partly in-situ high temperature experi-ments) of mixed perowskite crystals and other substances

Technical Mineralogy
Prof. Dr. G. Klöss

  • Detection and investigation of nanocrystals in natural glasses

Physical Crystallography
Doz. Dr. V. Geist

  • Investigation of the constitution and real structure of iron meteorites

Real Structure and Electron Microscopy
PD Dr. G. Wagner

  • Characterization of the defect structure of A(III)B(V)- and A(II)B(VI)-semiconductor thin films and nano-structures by electron microscopy (TEM, HRTEM, CBED,TEM-EDS)
  • Characterization of multinary chalcogenide thin films, bulk material and determination of the two-phase region for mixed chalcogenide com-pounds
  • Investigation of sulfosalts (in particular cylindrite) by electron microscopy

Mineralocigal–petrographic Collection
Curator Dr. H.-J. Höbler

  • Characterization and cataloging. Assembling of the new collection “Technical mineralogy”
  • Characterization of natural and synthetical semiconductor materials using the electron microprobe

Institute of Organic Chemistry

Natural Product and Bioorganic Chemistry
Prof. Dr. A. Giannis

  • Angiogenesis: Benzodiazepines and Piperazinones as RGD-mimetics
  • Design and Synthesis of Inhibitors of Methionine-Aminopeptidase-Type 2 (MetAP-2)
  • Sphingomyelinase and Apoptosis: Scyphostatine and Ceramide-analogues as Sphingomyelinaseinhibitors
  • Cell-Signalling, Receptor-Tyrosine-Kinases (RTKs): Development and biological investigation of novel inhibitors of RTKs
  • Protein-Lipidation: Inhibitors of Proteine-Palmitoyl-Thioesterase (peptidomimetics)
  • Inhibitors of the Sialic Acid Biosynthesis: Carbohydrate-analogues as inhibitors of Sialic Acid Biosynthesis
  • Development of new methods for oxidation, polymer-supported reagents.
  • Established assays for biological evaluation:
    Chorioallantois-Membrane-Assay (CAM-Assay)
    Proliferation - and Migration-Assay (HUVEC)
    Cell based "v(3-Assay, Sphingomyelinase-Assay
    Different RTKs-ELISAs as: VEGFR (flt-4 and KDR), EGFR, Erb2-R, Tie-2, IGF1-R; FGF-R.

Prof. Dr. D. Sicker
within the working group of Prof. Dr. A. Giannis

  • Isolation and Syntheses based upon the White Biotechnology for Green Chemistry concept
  • Formation and metabolic changes of benzoxazinoids from plants: their structural elucidation and contributions to the synthesis of plant own allelo chemicals

Organic Chemistry and Heterocyclic Chemistry
Prof. Dr. C. Schneider

  • Investigation of the silyloxy-Cope rearrangement of aldol products as syn-thetic method in organic chemistry
  • Total synthesis of the microtubuli-stabilizing marine natural product (+)-pelorusid A and investigation of structure-activity relationship with ana-logues
  • Total synthesis of hydroxyphthioceranic acid – the major component of sulfolipid SL-1 – through a novel and highly convergent synthesis strategy
  • Catalytic, enantioselective opening reaction of meso-epoxides for the synthesis of chiral, enantiomerically enriched fine chemicals
  • Catalytic, enantioselective opening reaction of meso-aziridines for the synthesis of chiral, enantiomerically enriched fine chemicals
  • Aldol-Tishchenko reactions of ketone aldols as enol equivalents for the direct, catalytic and enantioselective synthesis of polyhydroxylated com-pounds
  • Organocatalytic domino reactions towards the synthesis of enantiomeri-cally pure heterocyclic compounds
  • Brønstedt-acid-catalyzed, enantioselective, vinylogous Mukaiyama-Mannich Reactions towards the rapid assembly of enantiomerically highly enriched N-heterocycles
  • Brønstedt-acid-catalyzed, enantioselective, vinylogous Mukaiyama-Michael Reactions
  • Enzyme-catalyzed synthesis of fine chemicals

Chemical Diversity and Function
Prof. Dr. R. Breinbauer

  • Synthesis of libraries of heterocycles of high structural and functional di-versity
  • Synthesis of inhibitors of enzymes of the phenazine-biosynthesis pathway
  • Development of reductivly cleavable linker
  • Development and improvement of transition metal catalyzed synthetic methods

Heterocyclic Chemistry
Prof. Dr. B. Schulze

  • Synthesis of heterocyclic systems via sequential processes and ring trans-formations of heterocyclic compounds. Development of new leads for pharmaceuticals, pesticides and materials
  • Heterocycles as building blocks for macrocycles and in oxidation reactions
  • S,N-Heteroaromatic cations in oxidation reactions to hydroperoxy-functionalized sultams and sultims as oxygen transfer reagents
  • Functionalized N.N´-bisazaheterocycles with sulfonamid structure by oxi-dation of S,N-heteroaromatic salts
  • Reactions of S,N-heteroaromatic salts with base to 2-Imino-2H-thietes and isothiazol-3-ylidenes

Organic Chemistry/Catalysis
Prof. Dr. C. B. W. Stark

  • Catalytic oxidative cyclizations for the synthesis of diastereomerically and enantiomerically pure oxygen-heterocycles
  • Sequential catalysis using Ruthenium-catalysts
  • New oxidation reactions using Ruthenium-catalysts
  • Activation and catalysis using unusual Lewis-bases
  • Synthesis of natural products and bioactive analogues

Theoretical Organic Chemistry
PD Dr. S. Immel

  • DFT and ab initio investigations on reaction mechanisms
  • Structural and conformational analysis of natural products
  • Molecular host-guest inclusion complexes and analysis of their properties

Wilhelm Ostwald Institute of Physical and Theoretical Chemistry

Physical Chemistry I
Prof. Dr. H. Morgner
Research Areas:

  • Characterization of the molecular structure of fluid interfaces in equilib-rium and as function of time using the methods of surface analytics
  • Adsorption of oxygen on metal surfaces and and oxide formation (surface analysis)
  • Computer simulation (Molecular Dynamics)
  • thermodynamical treatment of interfaces, diffusion beyond Fick's law
  • Characterization of interfaces (liquid/gas, liquid/liquid and solid liquid) using interface tension and contact angle measurements
  • Thermodynamical characterisation and prediction of the adsorption of fluid multicomponent mixtures at liquid/solid and liquid/gas interfaces
  • Experimental and theoretical investigation of the phase behavior in systems of the type: surfactant + water + oil + cosurfactant
  • Development of thermodynamical methods for the calculation of interface properties (tension, profiles, segregation)
  • Characterization of the catalytic activity and selectivity of zeolithes
  • Characterization of the molecular structure of adsorbates in zeolithes
  • the synthesis of ordered nanoporous silicas (SBA-15, SBA-16 etc.) and car-bons (CMK-3 etc.)
  • the application of ordered nanoporous solids in chemical industry
  • the adsorption of fluid mixtures on solids
  • the calculation of wetting quantities from adsorption data
  • Identification of protein modifications as a result of oxidative stress

Methods:

  • MIES (Metastable Induced Electron Spectroscopy) at liquid surfaces, ARUPS/ARXPS: measurement of concentration depth profiles at fluid inter-faces
  • ICISS und NICISS: concentration depth profiles of specific elements at liquid and polymer surfaces
  • Electron spectrometer MAX 100, equipped with XPS, UPS, MIES, ISS, SPA/LEED
  • Tensiometry (plate, ring, maximum bubble pressure, spinning drop), con-tact angle, DSC, viscometry, HPLC, densitometry, polarisation microscopy
  • Adsorption volumetry ASAP 2010
  • Lab size reactors in combination with gas chromatography
  • Temperature programmed desorption (TPD) with coupling to QMS
  • FTIR- and NIR-FT-Raman spectrometer (System 2000R) with temperature programmed diffuse reflection (Praying Mantis) (access to instrument)
  • Simultaneous thermal analysis (STA-QMS-System 409/403, Netzsch) (access to instrument)
  • Reactivity in water/surfactant interfaces, influence on the reactivity
  • Computer simulation for modelling of adsorption equilibrium in micropor-ous solids
  • the characterization of solid surfaces by means of adsorption, thermo-desorption (SCTA) and microcalorimetry

Dr. I. Konovalov

  • Grow and properties of AgIn5S8/CuInS2/CuI p-I-n double heterostructure:
    - molecular beam epitaxy of ternary sulfides
    - determination of the band diagram and in particular of the band offsets at interfaces between CuI and various indium sulfides
    - electrical and optical properties of the heterostructure
  • Defect spectroscopy studies in semiconductors using synchrotron radiation

Physical Chemistry II
Prof. Dr. R. Denecke

  • Chemical reactivity, electronic and geometrical structure of surfaces of solids
  • Chemical modification and lateral structuring of metals and oxides by layer deposition with molecular beam sources, oxidation, absorption, electrochemical as well as photo- and electronbeam-induced reactions
  • Exploration of new spectroscopic and microscopic methods: angle- and polarisation-resolved X-ray emission spectroscopy applying synchrotron radiation sources
  • In-situ X-ray photoelectron spectroscopy in combination with a supersonic molecular beam apparatus to investigate adsorption and reactions on flat and stepped metal surfaces
  • Molecular beam investigations to measure sticking coefficients
  • Study of multiferroic layer systems to characterise and optimise the geo-metric and magnetic properties

Theoretical Chemistry
Prof. Dr. B. Kirchner, PD Dr. C. Engler

  • First-principles simulations, electronic structure calculations, and simula-tions: explicit relativistic description, methods with linear scaling, cluster-method, cooperative effects, intermolecular forces
  • Liquids, solvents and solvent effects: neoteric solvents, ionic liquids, asso-ciated liquids, hydrophobic hydration
  • Thermodynamic properties from theoretical calculations: static quantum-chemical methods, quantum cluster equilibrium theory, entropy
  • Computation chemistry: Nitrogenase Model-Complexes, cluster studies, aromaticity, green chemistry, CO2 and methane activation, su-pramolecular chemistry, template chemistry
  • Development of a new catalyst for synthesis of carbamins
  • Quantumchemical investigations to the formation, the stability, and struc-tural and electronic properties of ternary and quaternary GaBAs-, GaBP-, GaInBAs-, and GaInBP-semiconductor alloys.

Institute of Technical Chemistry

Prof. Dr. H. Papp

  • Immobilization of Salen complexes in mesoporous materials
  • Templated synthesis of porous carbon materials
  • Modification of carbon materials with metal compounds
  • Heterogeneously catalyzed transformation of hydrocarbons
  • Environmental catalysis – DENOX of waste gases
  • Investigation of elementary steps of heterogeneous catalytic processes
  • Surfaces analytical investigation of catalysts
  • Synthesis and modification of solid catalysts
  • Development of a virtual laboratory course in chemical engineering and unit operations

Prof. Dr. R. Gläser

  • Heterogeneous catalytis of conversions relevant to the refining, petro-chemical and fine chemical industries
  • Environmental catalysis - VOC abatement, waste water treatment
  • Investigation of elementary steps of processes on solid surfaces
  • Surface analysis of solid catalysts
  • Preparation of catalysts with defined nanoporosity (micro- and mesoporous materials)
  • Supported metal catalysts
  • Redox molecular sieves
  • “Green” solvents for heterogeneous catalysis (supercritical fluids, gas-expanded liquids, ionic liquids)
  • Development of a virtual laboratory course in chemical reaction engi-neering and unit operations

Prof. Dr. W.-D. Einicke

  • Synthesis, modification and characterization of mesoporous and micro-porous adsorbents
  • Adsorption and diffusion of gases and liquids in adsorbents
  • Microwave-induced catalytic combustion

PD Dr. C. Breitkopf

  • Heterogeneously catalyzed conversion of hydrocarbons
  • Environmental catalysis – DeNOx on Fe-modified ZSM-5 zeolites
  • Template synthesis of transition metal oxides
  • Investigation of elementary steps in heterogeneous catalysis
  • Surface science investigations on catalytic systems
  • Synthesis and modification of solid catalytic systems
  • Transport phenomena in porous catalysts
  • Modelling of combined diffussion and reaction processes

Prof. Dr. M. R. Buchmeiser

  • Synthesis of transition metal-based photoinitiators
  • Controlled (“living”) (photo-) polymerization from and to surfaces
  • Immobilization of organometallic catalysts, surface modification of meso- and macroporous systems, applications in catalysis (Mo, Ru, Rh, Ir, Ni, Pd, Pt, Cu catalyzed reactions)
  • Nanoparticle-modified polymer layers, functional nano-composites with radiation-curable polymers
  • New transition metal complexes for living ring-opening metathesis polym-erization (ROMP) of functional monomers
  • Living cyclopolymerisation of heptadiynes, synthesis of conjugated poly-mers, electrooptical devices and sensors
  • Synthesis of new functional (monolithic) separation media for the analysis of biologically and medically relevant compounds (DNA, proteins, oli-gonucleotides)
  • Monolithic materials for regenerative medicine
  • Synthesis of functional hybrid-polymers by switchable transition metal complexes
  • Design, synthesis and evaluation of new supported catalytic systems on a molecular base (supported C-C, C-Si, C-N coupling catalysts)
  • Primary processes and mechanisms of radiation-induced polymerisation and crosslinking (real-time FTIR spectroscopy, laser photolysis, pulse radio-lysis)
  • UV curing with eximer radiation
  • Radiation-curable functional layers
  • Process control with NIR spectroscopy
  • Microstructures by radiation-curable polymers
  • Plasma Enhanced Chemical Vapour Deposition (PECVD)

Interdisciplinary Group Time-resolved Spectroscopy

  • Elementary processes of the ionisation and oxidation of organic substances and mechanisms of effects of antioxidants in low-molecular systems and polymers
  • Electron transfer processes in polar and non-polar low-molecular solutions
  • Study of oxidative processes in lipids and model membranes
  • Radical reactions in biological model systems (building unites of nucleic acids, amino acids and peptides)
  • Methodical advancement of time-resolved spectroscopic methods and measuring procedures

Department of Chemistry Teaching

  • Investigation of pupils` scientific reasoning abilities and of possibilities to improve the reasoning competence
  • Investigation of pupils` conceptual understanding of chemistry and the effect of experiments to produce conceptual change
  • Development and evaluation of an experimental approach for chemistry beginners based on the principles of learning theories
  • Development of experimentally based, problem-oriented concepts for chemistry lessons integrating biological principles and methods
  • Investigation of pupils` integrative reasoning abilities in the context of “learning at stations”
  • Development and improvement of school experiments

Institute of Non-classical Chemistry

  • Determination of kinetic and thermodynamic process data
  • Simulation of technical processes in lab scale
  • Gas adsorption of pure components and mixtures on microporous solids
  • Investigation of properties of gases and supercritical fluids
  • Adsorption and desorption of vapors (e.g. hydrocarbons) in porous media like activated carbon or zeolites
  • Determination of break through curves in adsorber beds
  • Solubility of gases and vapors in polymers
  • Characterization of nanoporous materials for industrial application
  • Production of nanoporous materials by a new pressure change technique
  • Determination of absolute and relative coking rates in thermal processes as criterion for the characterisation of high-temperature materials, feed-stocks and additives
  • Investigations of coke formation on catalysts at combustion processes
  • Separation of products using pure or modified supercritical fluids
  • Investigation of geochemical and environmental processes in natural and anthropogenic influenced spheres
  • Identification of Natural Attenuation (NA-) Processes in fluids of lignite min-ing dumps
  • Source identification of pollutants by combination of chemical and stable isotope analysis
  • Investigations of isotope variations of the light elements as natural tracers
  • Degradation of pollutants in ground water by catalytic oxidation and catalytic oxidation combined with microbiology
  • Stimulation of chemical reactions using microwave and ultrasound
  • Development of analytical methods for determination of harmful substances in used wood, soil and contaminated water
  • Development of new analytical methods and techniques for derivatisa-tion for characterisation of valuable substances in natural material and drugs
  • Degradation of pollutants in high contaminated waste water by wet oxi-dation treatment
  • Investigations of adsorptive removal of pollutants in contaminated water
  • Extraction and characterisation of secondary metabolites from biological matrices
  • Increase of efficiency and permeat flow of membrane systems by using of impulse units
  • Development of an adsorption unit for decalcification of water
  • Splitting of biogas into carbon dioxide and methane by absorption tech-nologies

Center for Biotechnology and Biomedicine / Institute of Bioanalytical Chemistry

Prof. Dr. R. Hoffmann

  • Mass spectrometrical techniques to analyze posttranslational modifications in peptides and proteins
  • Characterization of the Tau phosphorylation pattern
  • Characterization of hydroxylated proline and lysine residues in collagens
  • Analysis of non-abundant proteins in serum
  • Synthesis and analysis of glycated peptides and proteins
  • Development of antimicrobial active peptides with respect to protease stability
  • Novel luminescence dyes to detect and to quantify proteins
  • Identification of protein modifications as a result of oxidative stress

Prof. Dr. N. Sträter

  • Enzymes in biocatalytic applications and as drug targets
  • Structural analysis of biological macromolecules by single crystal X-ray diffraction
  • Catalytic mechanisms of metalloenzymes
  • Structural biology of extracellular signaling via nucleotides
  • Domain motion and enzyme function
  • Structure determination of pharmacologically and biotechnologically relevant proteins

 

 
Home Zusammenstellung: Forschungskontaktstelle, 27.08.2008