Publications

During the duration of the GIPIO project several publications evolved. The following list includes the published papers so far.

Publications 2011

Horstmann A, Busse FP, Mathar D, Müller K, Lepsien J, Schlögl H, Kabisch S, Kratzsch J, Neumann J, Stumvoll M, Villringer A, Pleger B: Obesity-Related Differences between Women and Men in Brain Structure and Goal-Directed Behavior. Front Hum Neurosci. 2011;5:58. Epub 2011 Jun 10

Hollmann M, Hellrung L, Pleger B, Schlögl H, Kabisch S, Stumvoll M, Villringer A, Horstmann A: Neural correlates of the volitional regulation of the desire for food. Int J Obes (Lond). 2011 Jun 28. doi: 10.1038/ijo.2011.125. [Epub ahead of print]

Mueller K, Anwander A, Möller HE, Horstmann A, Lepsien J, Busse F, Mohammadi S, Schroeter ML, Stumvoll M, Villringer A, Pleger B: Sex-dependent influences of obesity on cerebral white matter investigated by diffusion-tensor imaging. PLoS One. 2011;6(4):e18544.

Tough IR, Forbes S Tolhurst R, Ellis M, Herzog H, Bornstein JC & Cox HM (2011). Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit by differentially via Y1 and Y2 receptors. Br J Pharmacol. 164, 66-79

Bellmann-Sickert K, Elling CE, Madsen AN, Little PB, Lundgren K, Gerlach LO, Bergmann R, Holst B, Schwartz TW, Beck-Sickinger AG.Long-acting lipidated analogue of human pancreatic polypeptide is slowly released into circulation. J Med Chem. 2011 Apr 28;54(8):2658-67. Epub 2011 Mar 31.

Siversen B, Lang M, Frimurer TM, Holliday ND, Bach A, Els S, Engelstoft MS, Petersen PS, Schwartz TW, Beck-Sickinger AG, Holst B. Unique interaction pattern of a functionally biased ghrelin receptor agonist. J Biol Chem. 2011 Mar 14. [Epub ahead of print]

Publications 2010

Cox HM, Tough IR, Woolston AM, Zhang L, Nguyen AD, Sainsbury A & Herzog H (2010)  Peptide YY is critical for acylethanolamide receptor Gpr119-induced activation of gastrointestinal mucosal responses.  Cell Metabolism, 11, 532–542.

• with a Preview by Schwartz TW & Holst B (2010)
  An enteroendocrine full package solution. Cell Metabolism, 11, 445–447.

Mokrosiński J. and Holst B. Modulation of the constitutive activity of the ghrelin receptor by use of pharmacological tools and mutagenesis. Methods Enzymol. (2010) 484: 53-73

Els, Sylvia; Beck-Sickinger, Annette G.; Chollet, Constance (2010). Ghrelin receptor: high constitutive activity and methods for developing inverse agonists. Methods Enzymol.; 485: 103–21.

Bellmann-Sickert K, Beck-Sickinger AG (2010). Peptide drugs to target G protein-coupled receptors. Trends Pharmacol Sci.31 S.434–41.

Schloegl H, Percik R, Horstmann A, Villringer A, Stumvoll M (2010) Effects of Gut Peptides and Dietary Substrates on appetite – Behavioral and Neuroimaging Studies in Humans. Diabetes Metab Res Rev. 2011 Feb;27(2):104-12.

Lohmann G, Margulies DS, Horstmann A, Pleger B, Lepsien J, Goldhahn D, Schloegl H, Stumvoll M, Villringer A, Turner R (2010) Eigenvector centrality mapping for analyzing connectivity patterns in fMRI data of the human brain. PLoS One. 2010 5(4):e10232.

Citable abstracts at meetings

N Jolly, C Elling, P Little, LO Gerlach TW Schwartz, HM Cox (2010). Functional activity of Y2/Y4 receptor agonists for the treatment of obesity. Br J Pharmacol. http://www.pa2online.org/abstracts/vol8issue1abst072P.pdf

N Jolly, R Tolhurst, A Beck-Sickinger, TW Schwartz, HM Cox (2010). Ghrelin receptor expression and activities in the mouse gastrointestinal tract. Br J Pharmacol. http://www.pa2online.org/abstracts/vol8issue1abst074P.pdf

Publications 2009

Petersen PS, Woldbye DPD, Madsen AN, Egerod KL, Jin C, Lang M, Rasmussen M, Beck-Sikinger A and Holst B: In vivo Characterisation of High Basal Signalling from the Ghrelin Receptor. Endocrinology (2009) 150: 4920–4930

Chollet C, Meyer K, Beck-Sickinger AG. Ghrelin – a novel generation of anti-obesity drug: design, pharmacomodulation and biological activity of ghrelin analogues. J Pept Sci. 2009 Nov;15(11):711–30.

Busse FP, Mueller K, Horstmann A, Stumvoll M, Kratzsch J, Villringer A: Structural changes in the reward system of patients with obesity – A morphometric analysis using DARTEL. Neuroimage, 47, Suppl. 1, S39–S41.

Poster

Schloegl H, Lepsien J, Horstmann A, Kabisch S, Busse F, Mueller K, Pleger B, Villringer A, Stumvoll M (2009) Brain Responses to Visual Food and Non-Food-Stimuli in Lean Subjects in Fasted and in Sated State. Neural Mechanisms of Ingestive Behavior, Poster Presentation, 15.–16.10.2009, Chicago, USA.

Kabisch S, Horstmann A, Schloegl H, Percik R, Busse F, Lepsien J, Mueller K, Pleger B, Stumvoll M, Villringer A (2009) Investigation of Hunger-Related Behaviour in Humans: Normalized and Calorifically Classified Visual Food Stimuli Improve Specificity. Research Festival University of Leipzig, Poster Presentation, 18.12.2009, Leipzig, Germany.