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Publications
Kirsten H, Petit-Teixeira E, Scholz M, Hasenclever D, Hantmann H, Heider D, Wagner U, Sack U, Teixeira VH, Prum B, Burkhardt J, Pierlot C, Emmrich F, Cornelis F, Ahnert P:
Association of MICA with rheumatoid arthritis independent of known
HLA-DRB1 risk alleles in a family-based and a case control study. Arthritis Res Ther. 2009 May 1;11(3):R60. [Epub ahead of print]
PMID: 19409079
Kirsten H, Burkhardt J, Hantmann H, Hunzelmann N, Vaith P, Ahnert P, Melchers I: 5HT2A Polymorphism His452Tyr in a German Caucasian Systemic Sclerosis population. Arthritis Res Ther.
accepted for publication Jan. 2009
Kirsten H, Petit-Teixeira E, Hantmann H, Reichardt J, Burkhardt J, Emmrich F, Cornelis F, Ahnert P:
A family based study does not support association of a functional
polymorphism in the gene for endothelial nitric oxide synthase with
risk for rheumatoid arthritis. Scand J Rheumatol. 2009 Mar 2:1-2. [Epub ahead of print]
PMID: 19255933
Wilcke A, Weissfuss J, Kirsten H, Wolfram G, Boltze J, Ahnert P: The role of gene DCDC2 in German dyslexics. Ann Dyslexia. 2009 Feb 24. [Epub ahead of print]
PMID: 19238550
Jaen O, Petit-Teixeira E, Kirsten H, Ahnert P,
Semerano L, Pierlot C, Cornelis F, Boissier MC, Falgarone G: No
evidence of major effects in several Toll-like receptor gene
polymorphisms in rheumatoid arthritis. Arthritis Res Ther.
2009;11(1):R5. Epub 2009 Jan 13
PMID: 19134200
Krupp W, Klein C, Koschny R, Holland H,
Seifert V, Meixensberger J: Assessment of neuropsychological parameters
and quality of life to evaluate outcome in patients with surgically
treated supratentorial meningiomas. Neurosurgery. 2009 Jan;64(1):40-7;
discussion 47.
PMID: 19145155
Melchers I, Ahnert P: [Relevance of the gene variant PTPN22 620W for rheumatology.]. Z Rheumatol. 2008 Oct 29. [Epub ahead of print]
PMID: 18956205
Kirsten H, Blume M, Emmrich F, Hunzelmann N, Mierau R, Rzepka R, Vaith P, Witte T, Melchers I, Ahnert P: No association between Systemic Sclerosis and the C77G Polymorphism in the Human PTPRC (CD45) Gene. J Rheumatol. 2008 Jul 15.
PMID: 18634151
Krupp W, Holland H, Koschny R, Bauer M, Schober R, Kirsten H, Livrea M, Meixensberger J, Ahnert P:
Genome-wide genetic characterization of an atypical meningioma by
single-nucleotide polymorphism arrayebased mapping and classical
cytogenetics. Cancer Genet Cytogenet. 2008 Jul 15;184(2):87-93.
PMID: 18617056
Koschny R, Sykora J, Walczak H, Ganten TM, Haas TL, Sprick MR, Holland H, Ahnert P,
Krupp W, Meixensberger J, Bauer M: Bortezomib-mediated upregulation of
TRAIL-R1 and TRAIL-R2 is not necessary for but contributes to
sensitization of primary human glioma cells to TRAIL. Clin Cancer
Res. 2007; 13: 6541-6542.
Ahnert P, Kirsten H: Association of ITGAV Supports Role of Angiogenesis in Rheumatoid Arthritis. Arthritis Res Ther. 2007 Oct 31;9(5):108.
PMID: 18001496
Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Schober R, Kirsten H, Ganten TM, Ahnert P: Cytogenetic and molecular biological characterization of an adult medulloblastoma. Cancer Genet Cytogenet. 2007 Oct; 178(2):104-113.
PMID: 17954265
Koschny R, Holland H, Sykora J, Haas TL, Sprick MR, ganten TM, Krupp W, Bauer M, Ahnert P,
Meixensberger J, Walczak H: Bortezomib sensitizes primary human
astrocytoma cells of WHO grade I - IV for TRAIL-induced apoptosis. Clin
Cancer Res. 2007 Jun; 13: 3403-3412.
PMID: 17545549
Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Kirsten H, Ahnert P: Comprehensive cytogenetic characterization of an esthesioneuroblastoma. Cancer Genet Cytogenet. 2007 Feb;173(2):89-96.
PMID: 17321323
Mahr S, Kirsten H, Müller B. Reply to Loughlin et al.: Am J Hum Genet. 2007 Feb;80:386-387.
Hartig W, Stieler J, Boerema AS, Wolf J, Schmidt U, Weissfuss J,
Bullmann T, Strijkstra AM, Arendt T.: Hibernation model of tau
phosphorylation in hamsters: selective vulnerability of cholinergic
basal forebrain neurons - implications for Alzheimer's disease. Eur J Neurosci. 2007 Jan;25(1):69-80.
PMID: 17241268
Kirsten H, Teupser D, Weissfuss J, Wolfram G, Emmrich F, Ahnert P:
Robustness of single base extension against mismatches at the site of
primer attachment in a clinical assay. J Mol Med. 2007 Apr;85(4):361-9.
PMID: 17160404
Kirsten H, Dienst S, Emmrich F, Ahnert P:
CalcDalton: a tool for multiplex genotyping primer design for
single-base extension reactions using cleavable primers. Biotechniques.
2006 Feb;40(2):158, 160, 162.
PMID: 16526404
Koschny R, Holland H,
Koschny T, Vitzthum HE: Comparative genomic hybridization pattern of
non-anaplastic and anaplastic oligodendrogliomas - A meta-analysis.
Pathol Res Pract. 2006;202(1):23-30.
PMID: 16356658
Ahnert, P., Picha, K.
M., and S. S. Patel: 2000, A ring-opening mechanism for DNA binding in
the central channel of the T7 helicase-primase protein, EMBO J.
19(13):3418-27.
PMID: 10880454
Picha, K. M., Ahnert,
P., and S. S. Patel: 2000, DNA binding in the central channel of
bacteriophage T7 helicase-primase is a multistep process. Nucleotide
hydrolysis is not required. Biochemistry 30;39(21):6401-9.
PMID: 10828954
Ahnert, P., and S. S.
Patel: 1997, Asymmetric Interactions of Hexameric Bacteriophage T7 DNA
Helicase with the 5´ - and 3´ -Tails of the Forked DNA Substrate. J.
Biol. Chem. 272(51):32267-32273.
PMID: 9405431
Books
Geistlinger J, Ahnert P:
Large-scale Detection of Genetic Variation: The Key to Personalized
Medicine, Kapitel 3 in: Modern Biopharmaceuticals (Jörg
Knäblein), Wiley-VCH, (2005) 71-98, ISBN: 352731184X
Knäblein, Editor
Ahnert, P.:
Contribution to three articles (Acetobacter, Candida Introduction,
Gluconobacter) in: Robinson “Encyclopedia Of Food Microbiology”, Academic
Press, 1999, ISBN: 0122270703
Commentaries
Ahnert P: Phänotypen, Genotypen und biologische Komplexität. VDI Ingenieur-Nachrichten 3 (2005) 15-16.
Ahnert P: Veranlagung in komplexen Erkrankungen. Bioforum 10 (2004) 38-39
Abstracts and Conferences
Ahnert P: Genomweite hochauflösende molekulare Zytogenetik.
In: 58. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie, 26.-29. April 2007, Leipzig. Seminar Zytogenetik
(http://www.dgnc.de/dgnc2007/index.php?site=tag&nav=49&SID=111&lan=d)
Holland H: Zytogenetische Analyse neuroepithelialer Tumore.
In: 58. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie, 26.-29. April 2007, Leipzig. Seminar Zytogenetik
(http://www.dgnc.de/dgnc2007/index.php?site=tag&nav=49&SID=111&lan=d)
Kirsten H, Ahnert P,
Dummler J, Hunzelmann N, Vaith P, Melchers I: Genetic association of
progressive systemic sclerosis (SSC) with PTPN22 polymorphisms. Ann Rheum Dis. March 1st 2007; 66: A54-A54 154 Suppl. 1
Wilcke A, Weißfuß J, Kirsten H, Ahnert P: Genetic basics of dyslexia.
In: 5th Leipzig Research Festival for Life Sciences 2006
Universität Leipzig, Leipzig (2006); 210
ISBN 3-9810760-1-X
Holland H, Koschny R, Krupp W, Meixensberger J, Ahnert P:
Detection of de novo chromosomal aberrations in an
esthesioneuroblastoma using cytogenetic and molecularcytogenetic
techniques.
In: 5th Leipzig Research Festival for Life Sciences 2006
Universität Leipzig, Leipzig (2006); 222
ISBN 3-9810760-1-X
Kirsten H, Wolfram G, Reichardt J, Anders D, Hofmann K, Ruhland S, Ahnert P: Evidence for an additional risk factor in the HLA region modifying the
risk from known HLA-DRB1 risk alleles in Rheumatoid Arthritis.
In: 5th Leipzig Research Festival for Life Sciences 2006
Universität Leipzig, Leipzig (2006); 225
ISBN 3-9810760-1-X
Weißfuß J, Kirsten H, Ahnert P: A Candidate gene Association Study using the Genolink System revealed presumptive Associations with Rheumatoid Arthritis.
In: 5th Leipzig Research Festival for Life Sciences 2006
Universität Leipzig, Leipzig (2006); 243
ISBN 3-9810760-1-X
Jaen O, Petit-Teixeira, E, Kirsten H, Pierlot C, Ahnert P,
Cornelis F, Boissier MC, Falgarone G: Lack of association between Tlr
genes in rheumatoid arthritis: A 6 member study of the TLR family.
In: Arthritis and Rheumatism Sep. 2006; 54 (9): S37-S38 Suppl. S
Holland H, Koschny R, Krupp W, Meixensberger J, Ahnert P: Comprehensive Cytogenetic Characterization of an Esthesioneuroblastoma. Med Gen 2006;18: 50
Koschny R, Holland H, Sykora J, Sprick MR, Haas TL, Ganten TM, Krupp W, Bauer M, Ahnert P,
Meixensberger J, Walczak H: Bortezomib sensitizes primary human
esthesioneuroblastoma cells for TRAIL-induced apoptosis. GMS German
Medical Science 2006; GM06dkk379
Weißfuß J, Kirsten H, Wolfram G, Ahnert
P: A Candidate Gene Association Study using the Genolink Genotyping
System revealed presumptive Genetic Associations concerning Rheumatoid
Arthritis. Abstract Book Leipzig Research Festival for Life Sciences
2005, Universität Leipzig, (2005), 265, ISBN: 3-9810760-0-1
Hengstler
J, Hermes M, Schormann W, Brulport M Bussmann B, Ahnert P, Heinrich M,
Wilde A, Emmrich F, Braun JM: Induction of immunotolerance of
xenotransplanted human hepatocytic cell line into fully immunocompetent
C57BL6 mice using anti-CD4 monoclonal antibody induction therapy.
Abstract Book Leipzig Research Festival for Life Sciences 2005,
Universität Leipzig (2005), 8, ISBN: 3-9810760-0-1
Kirsten
H, Dienst S, Wolfram G, Ahnert P: New Assay design software and Assay
performance of GenoSNIP, a Single Base Extension / MALDI based SNP
genotyping technique. Abstract Book Leipzig Research Festival for Life
Sciences 2005, Universität Leipzig, Dezember 2005, 257, ISBN:
3-9810760-0-1
Ahnert P, Reichardt J, Kirsten H, et al.: Systematic genome wide functional evaluation of disease candidate genes. Ann Rheum Dis. 2005 Jul 3;64: 117-117 Suppl. 3
Ahnert P, Kirsten H, Ruhland S, et al.:
Application of the GENOLINK(TM) genotyping system in a candidate gene
association study in rheumatoide arthritis. Ann Rheum Dis. 2004 Jul
1;63: 116-116 Suppl. 1
Kirsten H, Strehlitz W, Zebisch V, Ahnert P: Dealing with a non perfect world: Robustness of SNP-genotyping to unknown DNA mutations interfering the assay.
In: 3rd Leipzig Research Festival for Life Sciences 2004
Universität Leipzig, Leipzig (2004); 127
ISBN 3-00-015269-5
Ahnert P: A
candidate gene association study in rheumatoid arthritis, strategies
for gene and polymorphism selection and an application of the genolink
genotyping system.
In: 3rd Leipzig Research Festival for Life Sciences 2004
Universität Leipzig, Leipzig (2004); 19
ISBN 3-00-015269-5
Fried C, Stadler PF, Ahnert P:
Correlations of divergence and diversity inferred from genome-wide
analysis of single nucleotide polymorphisms and phylogenetic footprints.
In: 3rd Leipzig Research Festival for Life Sciences 2004
Universität Leipzig, Leipzig (2004); 12
ISBN 3-00-015269-5
Reichardt J, Kirsten H, Rühle S, Oeser C, Blume M, Steiner A, Meier N, Möckel M, Ahnert P: Systematic genome wide functional evaluation of disease candidate genes.
In: 3rd Leipzig Research Festival for Life Sciences 2004
Universität Leipzig, Leipzig (2004); 8
ISBN 3-00-015269-5
Kirsten H, Hofmann K, Wolfram G, Ahnert P: SNP selection and assay design for a candidate gene genotype-phenotype association study in rheumatoid arthritis.
In: 2nd Leipzig Research Festival for Life Sciences 2003
Universität Leipzig, Leipzig (2003); 21
ISBN 3-928921-96-7
Nettikadan S, Ahnert P, Patel SS, et al.: Helicase-DNA interaction studied by atomic force microscopy Biophys J. 1998 Feb;74 (2): A186-A186 Part 2
Patel SS, Hingorani MM, Washington MT, Ahnert P, et al.: Mechanism of T7 DNA helicase Biophys J. 1998 Feb;74 (2): A334-A334 Part 2
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