Cell Techniques and Applied Stem Cell Biology

Sanja Pavlica

Dr. rer. nat. Sanja Pavlica

Reasearch projects
 

Effect of Erythropoietin (rhEPO) on neuronal protection and regeneration

Effect of Erythropoietin (rhEPO) on expansion of neuronal and liver progenitor cells

Effect of early cytokines on neuronal differentiation -neuronal-like differentiation of MSCs

Curriculum vitae
            

Education:

July 2005 - Ph.D. (Dr. rer.nat.), Faculty of Biology, Pharmacy and Psychology, University of Leipzig, Germany

February 1999 - M.Sc. in Biochemistry, Faculty of Chemistry, University of Belgrade, Serbia

April 1993 - B.Sc. in Biochemistry, Faculty of Chemistry, University of Belgrade, Serbia

Publications:

Pavlica S, Milosevic J, Keller M, Schulze M, Piscioneri A, DeBartolo L, Darsow K, Bartel S, Lange H, Bader A. Erythropoietin enhances cell proliferation and survival of human fetal neuronal progenitors in normoxia. Brain Res. 2012 Feb 25. [Epub ahead of print]

Bader A, Peters O, Keller M, Pavlica S. (2011) Paracetamol treatment increases telomerase activity in rat embryonic liver cells (short communication). Pharmacol Rep. 2011 Nov;63(6):1435-41

Bader A, Pavlica S, Deiwick A, Lotkova H, Kucera O, Darsow K, Bartel S, Schulze M, Lange HA, Cervinkova Z. Proteomic analysis to display the effect of low doses of Erythropoietin on rat liver regeneration. Life Sci. 2011 Dec 5;89(23-24):827-33. Epub 2011 Aug 18.

Mofidi A, Bader A, Pavlica S. (2011) The use of Erythropoietin and ist Derivatives to Treat Spinal Cord Injury. Mini Rev Med Chem. 2011 Aug 1;11(9):763-70.

Bader A, Pavlica S, Deiwick A, Lotkova H, Kucera O, Darsow K, Bartel S, Schulze M, Lange HA, Cervinkova Z. Proteomic analysis to display the effect of low doses of Erythropoietin on rat liver regeneration. Life Sci. 2011 Dec 5;89(23-24):827-33. Epub 2011 Aug 18.

Pavlica S., Schmitmeier S, Gloeckner P, Piscioneri A, Peinemann F, Krohn K, Siegmud-Schulz M, Laera S, DeBartolo L, Bader A. Effects of native and NH3 plasma functionalized polimeric membranes on the gene expression profiles of primary hepatocytes. J Tissue Eng Regen Med. 2011 Jul 13. doi: 10.1002/term.453. [Epub ahead of print]

Mauth C, Deiwick A, Steffen A, Pavlica S, Bader A. The influence of oxygen supply on metabolism of neural cells cultured on gas-permeable PTFE foil. (2010) Biotechnol Prog. 2010 Nov-Dec;26(6):1724-32. doi: 10.1002/btpr.478

Giri S, Nieber K, Acikgöz A, Pavlica S, Keller M, Bader A. (2009) Telomerase activity and hepatic functions of rat embryonic liver progenitor cell in nanoscaffold coated small scale bioreactor. Mol Cell Biochem. 2010 Mar;336(1-2):137-49. Epub 2009 Oct 9

Pavlica S, Gebhardt R. (2009) Protective effects of flavonoidsand two metabolites against oxidative stress in neuronal PC12 cells. Life Sci. 2010 Jan 16;86(3-4):79-86. Epub 2009 Nov 3

Pavlica S, Gebhardt R. (2009) Comparison of uptake and neuroprotective potential of seven zinc-salts. Neurochem Int. 2010 Jan; 56(1):84-93. Epub 2009 Sep 24

Pavlica S, Gaunitz F, Gebhardt R. (2009) Comparative in vitro toxicity of seven zinc-salts towards neuronal PC12 cellls. Toxicol In Vitro. 2009 Jun;23(4):653-9. Epub 2009 Mar 21

Pavlica S, Piscioneri A, Peinemann F, Keller M, Milosevic J, Staeudte A, Heilmann A, Schulz-Siegmund M, Laera S, Favia P, DeBartolo L., Bader A. (2009) Rat embryonic liver expansion and differentiation on NH₃ plasma-grafted PEEK-WC-PU membranes. Biomaterials 30, 6514-6521, Epub 2009 Sep 1

Morawski M, Pavlica S, Seeger G, Grosche J, Kouznetsova E, Schliebs R, Brückner G, Arendt T. (2008) Perineuronal nets are largely unaffected in Alzheimer model Tg2576 mice. Neurobiol Aging. 2010 Jul;31(7):1254-6. Epub 2008 Oct 1

Brückner G, Szeöke S, Pavlica S, Grosche J, Kaczka J (2006). Axon initial segment ensheathed by extracellular matrix in perineuronal nets. Neuroscience, 138, 365-75

Brückner G, Pavlica S, Morawski M, Palacios AG, Reichenbach A (2006) Organization of brain extracellular matrix shows hallmarks of mammalian evolution in Chilean fat-tailed mouse opossum Thylamys elegans (Waterhouse, 1839) J Chem Neuroanat. 32, 143-58

Pavlica S., Gebhardt R. (2005): Protective effect of Ellagic and Chlorogenic acids against oxidative stress in PC12 cells. Free Radic Res 39 (12): 1377-90.

Marinovic V, Nedic O, Stanojevic N, Baricevic I, Pavlica S (2000). Correlation between prostate specific antigen and acid phosphatase. Yugoslav Medical Biochemistry, 19, 407-410.

Pavlica S, Cuperlovic M (1997): Elderberry (Sambucus nigra L) bark lectin: isolation, partial characterization and seasonal variations in a local variety. Archives of Biological Sciences, 49, (3-4), 23P-24P.

Conference Poster Presentations

Pavlica, S., Grosche, J., Brückner, G (2006):  Activated glial cells do not interfere with the development of perineuronal nets of extracellular matrix in midbrain slice cultures. 5. Biotechnologie -Tag an der Universität Leipzig, Germany, abstract 7.52.

Pavlica, S., Kouznetsova, E, Morawski M, Brückner G, Schliebs R, Arendt, T. (2006) Perineuronal extracellular matrix, activated microglia and amyloid plaques in transgenic Tg2576 mice. 5. Leipzig Research Festival, Germany, abstract 117.

Pavlica, S., Grosche, J., Brückner, G (2006):  Activated glial cells do not interfere with the development of perineuronal nets of extracellular matrix in midbrain slice cultures. 5. Biotechnologie -Tag an der Universität Leipzig, Germany, abstract 7.52.

Pavlica, S., Gebhardt, R. (2003): Protective effects of plant polyphenols in PC12 cells exposed to iron. 51 st Ann. Medicinal Plant Research, Kiel, Germany, abstract P156.

Pavlica, S., Gebhardt, R. (2003): Protective effects of plant polyphenols against oxidative injury in PC12 cells. 6th IBRO World congress of neuroscience, Prague, Czech Republic, abstracts 3367.

Gebhardt, R., Pavlica, S. (2003): Vergleichende Untersuchungen zu Aufnahme und zellulärer Wirkung von Zinksalzen an Hepatocytenkulturen - Ausgeprägte hepatoprotektive Eigenschaften von Zinkhistidin. 2. Biotechnologie -Tag an der Universität Leipzig, Germany, abstact 5.11.

Pavlica, S., Gebhardt, R. (2003): Strong antioxidant function of Zinc histidine in PC12 cells. Zinc signals 2003, 4th Annual International Conference, Abstract PS 9.1, Grand Cayman

Gebhardt, R., Pavlica, S. (2003): Uptake of different zinc salts into hepatocytes and comparison of their protective potential: Marked hepatoprotective effects of zinc-histidine. Zinc signals 2003, 4th Annual International Conference, Abstract PS 4.1, Grand Cayman

Pavlica, S.,  Bojic,  Z.,  Hajdukovic-Dragojlovic,  Lj., Cuperlovic, M. & Peumans, W.J. (1997): Study of human immunoglobulin microheterogeneity by lectin-based methods. INTERLEC 17, Würzburg, Germany, abstr. 132.

Hajdukovic-Dragojlovic, Lj.,  Pavlica, S. , Cuperlovic, M., Stajic, M. & Golubovic, G. (1995): Carbohydrate-deficient transferrin in some liver diseases determined by using lectin affinity chromatography. Third Meeting of the Balkan Clinical Laboratory Federation, Struga, Macedonia, abstr.105.

Gruden-Movsesijan, A., Cuperlovic, M., Pavlica, S. (1995): Levels of collectin, mannose-biding protein in sera of rats and man infected with Trichinella spiralis. First Balkan Immunology Conference, Belgrade, Yugoslavia, abstr. 272.