Publikationen (peer reviewed) Unsere Forschung in den Medien Sonstiges

Publikationen

2013

Microfluidic free-flow electrophoresis chips with an integrated fluorescent sensor layer for real time pH imaging in isoelectric focusing
S. Jezierski , D. Belder, S. Nagl, Chem. Commun., 2013,49, 904-906

2012

Chip-based separation devices coupled to mass spectrometry
S. Ohla, D, Belder*, Current Opinion in Chemical Biology, 2012, 16, 453–459

Monitoring on-Chip Pictet-Spengler Reactions by Integrated Analytical Separation and Label-Free Time-Resolved Fluorescence
S. Ohla,  R. Beyreiss, S. Fritzsche, P. Glaser, S. Nagl, K. Stockhausen, C. Schneider,  D. Belder*, Chem. Eur. J. 2012, 18, 1240 – 1246

Label-free real-time imaging in microchip free-flow electrophoresis applying high speed deep UV fluorescence scanning
S. Köhler, S. Nagl, S. Fritzsche, D. Belder*, Lab Chip, 2012, 12, 458-463

Micro free-flow electrophoresis with injection molded chips
S. Köhler, C. Benz, H. Becker, E. Beckert, V. Beushausen D. Belder*, RSC Adv., 2012, 2, 520-525

Poly(ethylene glycol)-coated microfluidic devices for chip electrophoresis
M. Schulze, D. Belder*, Electrophoresis 2012, Electrophoresis 2012, 33, 370–378

2011

Label-free analysis in chip electrophoresis applying deep UV fluorescence lifetime detection
R. Beyreiss, S. Ohla, S. Nagl, D. Belder*, Electrophoresis 2011, 32, 3108–3114.

Multistep liquid-phase lithography for fast prototyping of microfluidic free-flow-electrophoresis chips
S. Jezierski, L. Gitlin, S.Nagl, D. Belder*, Anal Bioanal Chem. 2011, 401, 2651–2656

Asymmetric Organocatalysis and Analysis on a Single Microfluidic Nanospray Chip
S. Fritzsche, S. Ohla, P. Glaser, D. S. Giera, M. Sickert, C. Schneider, and D. Belder*, Angew. Chem. Int. Ed., 2011, 50, 9467 –9470

Rapid quantitative determination of ephedra alkaloids in tablet formulations and human urine by microchip electrophoresis
D. Belder*, K. Tolba, S. Nagl, Electrophoresis 2011, 32, 440-447.

Chip electrophoresis of active banana ingredients with label-free detection utilizing deep UV native fluorescence and mass spectrometry
S. Ohla, P.Schulze, S. Fritzsche and D. Belder*, Analytical and Bioanalytical Chemistry, 2011, 399, 1853-1857.

PDMS free-flow electrophoresis chips with integrated partitioning bars for bubble segregation
S. Köhler, C. Weilbeer, S. Howitz, H. Becker, V. Beushausen and Detlev Belder*, Lab Chip, 2011, 11, 309-314.

Microfluidic chips for chirality exploration
S. Nagl, P. Schulze, S. Ohla, R. Beyreiss, L. Gitlin, D.Belder*, Anal. Chem. 2011, 83, 3232–3238.

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2010

An integrated on-chip sirtuin assay
S. Ohla, R. Beyreiss, G. K. E. Scriba, Y. Fan, D. Belder*,  Electrophoresis 2010 ,31, 3263-3267

Screening in One Sweep using the Slipchip
D. Belder, Angew. Chem. 2010,  49, 6484–6486

A New Weakly Basic Amino-Reactive Fluorescent Label for Use in Isoelectric Focusing and Chip Electrophoresis
P. Schulze, M. Link, M. Schulze, S. Thuermann, O.S. Wolfbeis, D. Belder,  Electrophoresis 2010, 31, 2749–2753

Chip electrophoresis with mass spectrometric detection in record speed
Stefanie Fritzsche, Peter Hoffmann and Detlev Belder*, Lab Chip 2010, 10, 1227–1230

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2009

Spray Performance of Microfluidic Glass Devices with Integrated Pulled Nanoelectrospray Emitters
Peter Hoffmann, Markus Eschner, Stefanie Fritzsche and Detlev Belder*, Analytical Chemisty, 2009 DOI:10.1021/ac9015038

Progress in microchip enantioseparations
Stefan Nagl, Philipp Schulze, Martin Ludwig and Detlev Belder*, Electrophoresis, 2009, 30 (16), 2765-2772

Rapid replication of master structures by double casting with PDMS
L. Gitlin, P. Schulze, D. Belder*, Lab Chip,2009, 9 (20), 3000-3002.

Towards an Integrated Chemical Circuit
D. Belder, Angew. Chem. Int. Ed. 2009, 48, 3736 – 3737.

New diode laser-excitable green fluorescent label and its application to detection of bovine serum albumin via microchipelectrophoresis
M. Link, P. Schulze, D. Belder*, O. Wolfbeis*, Microchim Acta, 2009, 166 (1-2), 183-188.

Label-free fluorescence detection for capillary electrophoresis and microfluidic chip-based techniques,
P. Schulze, D. Belder*, Anal. Bioanal. Chem., 2009, 393, 515-525.

2008

Impact of laser excitation intensity on deep UV fluorescence detection in microchip electrophoresis,
P. Schulze, M. Ludwig, D. Belder*, Electrophoresis, 2008, 29, 4894-4899.

2007

Two–photon excited fluorescence detection at 420 nm for label–free detection of small aromatics and proteins in microchip electrophoresis
P. Schulze, M. Schüttpelz, M. Sauer, D. Belder*, Lab Chip, 2007, 12,1841–1844.

Fast quantitative determination of diuretic drugs in tablets and human urine by microchip electrophoresis with native fluorescence detection
K. Tolba, D. Belder*, Electrophoresis, 2007, 28, 2934–2941.

Microfluidic glass chip with an integrated nanospray emitter for coupling to a mass spectrometer
P. Hoffmann, U. Häusig, P. Schulze, D. Belder*,  Angew. Chem. int. Ed., 2007, 4913–4916.

2006

Integrating chemical synthesis and analysis on a chip 
D. Belder,  Anal. Bioanal. Chem., 2006, 385, 416–418.

Coating of powder–blasted channels for high performance microchip electrophoresis
D. Belder*, F. Kohler, M. Ludwig, K. Tolba, N. Piehl, Electrophoresis, 2006, 27, 3277–3283.

Enantioselective catalysis and analysis on a chipVIP
Belder*, M. Ludwig, L.–W. Wang,  M. T. Reetz*, Angew. Chem. Int. Ed., 2006, 45, 2463 –2466.

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Enantioselektive Katalyse und Analyse auf einem Mikrochip
D. Belder*, M. Ludwig, L.–W. Wang, M. T. Reetz*, Angew. Chem., 2006, 118, 2523–2526.

2005

Mikrofluidik mit Tröpfchen
D. Belder, Angew. Chem., 2005,  117, 3587–3588.

Microfluidics with droplets
D. Belder, Angew. Chem. Int. Ed., 2005, 44, 3521–3522.

Deep UV laser–induced fluorescence detection of unlabeled drugs and proteins in microchip electrophoresis
P. Schulze, M. Ludwig, F. Kohler, D. Belder*, Anal. Chem., 2005, 77, 1325–1329.

2004

Subsecond chiral separations in microfluidic devices
N. Piehl, M. Ludwig, D. Belder*, Electrophoresis, 2004, 25, 3848–3852.

Separation of FITC–labeled amines by microchip electrophoresis on uncoated and PVA–coated glass chips with dimethyl sulfoxide based electrolyte 
S. J. O. Varjo, M. Ludwig, D. Belder*, M.–L. Riekkola*, Electrophoresis, 2004, 25, 1901–1906.

2003

Surface modification in microchip electrophoresis, review
D. Belder*, M. Ludwig, Electrophoresis, 2003, 24, 3595–3606.

Coated microfluidic devices for improved chiral separations in microchip electrophoresis
M. Ludwig, D. Belder*, Electrophoresis, 2003, 24, 2481– 2486.

Microchip electrophoresis for chiral separations, review
D. Belder*, M. Ludwig, Electrophoresis, 2003, 24, 2422–2430.

High–speed chiral separations on a microchip with UV–detection
M. Ludwig, F. Kohler, D. Belder*, Electrophoresis, 2003, 24, 3233–3238.

2002

Poly(vinyl alcohol) coated microfluidic devices for high performance microchip electrophoresis
D. Belder*, A. Deege , F. Kohler, M. Ludwig, Electrophoresis, 2002, 23, 3567–3573.

Design and performance of a microchip electrophoresis instrument with sensitive variable wavelength fluorescence detection D. Belder*, A. Deege, M. Maass, M. Ludwig, Electrophoresis, 2002, 23, 2355–2361.

2001

Crosslinked poly(vinyl alcohol) as permanent hydrophilic column coating for capillary electrophoresis
D. Belder*, A. Deege, H. Husmann, F. Kohler, M. Ludwig, Electrophoresis, 2001, 22, 3813–3818.

Electrokinetic effects in poly(ethylene glycol) coated capillaries induced by specific adsorption of cations
D. Belder*, J. Warnke, Langmuir, 2001, 17, 4962–4966.

Directed control of electroosmotic flow in non–aqueous electrolytes using poly(ethylene glycol) coated capillaries
D. Belder*, H. Husmann, J. Warnke, Electrophoresis, 2001, 22, 666.

2000-1992

Super–high–throughput screening of enantioselective catalysts by using capillary array electrophoresis
M.T. Reetz*, K.M. Kühling, A. Deege, H. Hinrichs, D. Belder*, Angew. Chem. Int. Ed.,  2000, 39, 3891–3893.

Influence of pH* of methanolic electrolytes on electroosmotic flow in hydrophilic coated capillaries
D. Belder*, K. Elke, H. Husmann, Journal of Chromatography A, 2000, 868, 63–71.

Use of coated capillaries for nonaqueous capillary electrophoresis
D. Belder*, K. Elke, H. Husmann, J. Microcolumn Separations, 1999, 11, 209–213.

CE/MALDI–MS of peptides and low molecular weight drugs using non–volatile buffers
D. Belder*, H. Husmann, J. Schöppenthau, G. Paulus, HRC, 1998, 21, 59–62.

Analysis of alkaloids by capillary electrophoresis and capillary electrophoresis/mass spectrometry
J. Stöckigt, M. Unger, D. Stöckigt, D. Belder in Alkaloids Chemical and Biological Perspectives, S. W. Pelletier, (Ed.), Vol. 12, Pergamon: New York, 1998, 289–341.

Analysis of rauwolfia alkaloids employing capillary electrophoresis/mass spectrometry
D. Stöckigt*, M. Unger, D. Belder, J. Stöckigt, Nat. Prod. Lett., 1997, 9, 265–272.

Alkaloid determination in crude extracts from cortex quebracho and opium applying capillary electrophoresis and capillary electrophoresis/mass spectrometry coupling
M. Unger, D. Stöckigt, D. Belder, J. Stöckigt*, Pharmazie, 1997, 52, 691–696.

General approach for the analysis of various alkaloid classes using capillary electrophoresis and capillary electrophoresis/mass spectrometry
M. Unger, D. Stöckigt, D. Belder, J. Stöckigt*, J. Chromatogr. A, 1997, 767, 263–276.

Capillary electrophoresis/mass spectrometry analysis of peptides with a non–aqueous buffer
D. Stöckigt*, D. Belder, Biol. Chem., 1997, 378, 20.

Analysis of basic pharmaceuticals by capillary electrophoresis in coated capillaries and on–line mass spectrometric detection
D. Belder*, D. Stöckigt*, Journal of Chromatography A, 1996, 752, 271–277.

Separation and identification of basic dendrimers using capillary electrophoresis on–line coupled to a sector mass spectrometer
D. Stöckigt*, G. Lohmer, D. Belder*, Rap. Commun. Mass Spectrom., 1996, 10, 521–526.

Mixed valent nickel and mangenese oxide ceramics – model systems with superconducting properties? D. Reinen*, U. Kesper, D. Belder, Journal of Solid State Chemistry, 1995, 116, 355–363.

Ionic and non–Ionic polymers as wall modifiers in capillary electrophoresis 
G. Schomburg*, D. Belder, M. Gilges, St.R Motsch, Journal of Capillary Electrophoresis, 1994, 1, 7.

Chiral separations of basic and acidic compounds in modified capillaries using cyclodextrin–modified capillary zone electrophoresis
D. Belder, G. Schomburg*, Journal of Chromatography A, 1994, 666, 351–365.

Modification of silica surfaces for CZE by adsorption of non–ionic hydrophilic polymers or use of radial electrical fields
D. Belder, G. Schomburg*, HRC, 1992