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Forschung - Research

Dr. B. Fuchs

Publications

 

  • 57. Fuchs, B. Analysis of phospholipids and glycolipids by thin-layer chromatography-matrix-assisted laser desorption and ionization mass spectrometry. J. Chromatogr. A 1259 (2012) 62-73.
  • 56. Fuchs, B., Müller, K., Paasch, U., Schiller, J. Lysophospholipids: Potential Markers of Diseases and Infertility? Mini-Rev. Med. Chem. 12 (2012) 74-86.
  • 55. Fuchs, B., Bresler, K., Schiller, J. Oxidative Changes of Lipids Monitored by MALDI MS. Chem. Phys. Lipids 164 (2011), 782-795.
  • 54. Fuchs, B., Schnapka-Hille, L., Schiller, J., Cross, M.A. Oxygen and Cytokine-Dependent Changes in Choline Phospholipid Saturation in Hematopoietitic Progenitor Cells Detected by MALDI-TOF Mass Spectrometry. Chem. Phys. Lipids 164 (2011) 636-642.
  • 53. Loewenbrück, K.F., Fuchs, B., Hermann, A., Brandt, M., Werner,, A., Kirsch, M., Schwarz, S., Schöler, H.R., Schwarz, J., Schiller, J., Storch, A. Proton MR Spectroscopy of Neural Stem Cells: Does the Peak at 1.28 ppm Function as a Biomarker for Cell Type or State? Rejuvenation Res. 14 (2011) 371-381.
  • 52. Eibisch, M., Zellmer, S., Gebhardt, R., Süß, R., Fuchs, B., Schiller, J. Phosphatidylcholine Dimers Can be Easily Misinterpreted as Cardiolipids in Complex Lipid Mixtures: A MALDI-TOF MS STUDY of Lipids from Hepatocytes. Rapid Commun. Mass Spectrom. 25 (2011) 2619-2626.
  • 51. Fuchs, B., Schiller, J. Thin-Layer Chromatography with Direct Mass Spectrometric Analyte Detection. In: Holčapek, M. and Byrdwell, C. (Eds.), Extreme Chromatography - Gaster, Hotter, Smaller, 1st edition, AOCS press Urbana (2011) 431-462.
  • 50. Wu J, Teuber K, Eibisch M, Fuchs B, Schiller J. Chlorinated and Brominated Phospholipids are generated under the Influence of the Fenton Reagent - A MALDI-TOF MS Study. Chem. Phys. Lipids 164 (2011) 1-8.
  • 49. Eibisch M, Fuchs B, Schiller J., Süß R, Teuber K. Analysis of Phospholipid Mixtures from Biological Tissues by Matrix-Assisted Laser Desorption and Ionization Time-of-Flight-Mass Spectrometry (MALDI-TOF MS): A Practical Training. J. Chem. Educ. 88 (2011) 503-507.
  • 48. Fuchs B, Süß R, Teuber K, Eibisch M, Schiller J. Lipid Analysis by Thin-Layer Chromatography - A review of the current state.J. Chromatogr. A in press.57. Bischoff A, Eibisch M, Fuchs B, Süß R, Schürenberg M, Suckau D, Schiller J. A simple TLC/MALDI Method to monitor Oxidation Products of Phosphatidylcholines and -ethanolamines. Acta Chromatogr. 1218 (2011) 2754-2774.
  • 47. Fuchs B,Teuber K, Nimptsch A, Nimptsch K, Süß R, Schiller J. Thin-layer chromatography with direct mass spectrometric analyte detection - A review of the progress achieved in the last five years. In: Srivastava, M.M. (Ed.) "High-Performance Thin-Layer Chromatography (HPTCL)." Springer, New York Dordrecht  Heidelberg London (2011) pp. 335-363. ISBN 978-3-642-14024-2.
  • 46. Leßig J, Fuchs B. HOCl-mediated glycerophosphocholine and glycerophosphoethanolamine generation from plasmalogens in phospholipid mixtures.
    • Lipids 45(2010) 37-51.
  • 45. Renner C, Zemitzsch N, Fuchs B, Geiger KD, Hermes M, Hengstler J, Gebhardt R, Meixensberger J, Gaunitz F.
    • Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model. Molecular Cancer 9 (2010) 2.
  • 44.Teuber K, Schiller J, Fuchs B, Karas M, Jaskolla T.
    • Significant Sensitivity Improvements by Matrix Optimization: A MALDI-TOF Mass Spectrometric Study of Lipids from Hen Egg Yolk. Chem. Phys. Lipids 163 (2010) 552-560.
  • 43. Fuchs B, Süß R, Schiller J. An Update of MALDI-TOF Mass Spectrometry in Lipid Research. Progr. Lipid Res. 49 (2010) 450-475.
  • 42. Fuchs B, Teuber K, Nimptsch A, Nimptsch K, Süß R, Schiller J.Thin-layer chromatography with direct mass spectrometric analyte detection - A review of the progress achieved in the last five years. In: Srivastava, M.M. (Ed.) "High-Performance Thin-Layer Chromatography (HPTCL)." Springer, New York Dordrecht Heidelberg London (2010) in press. ISBN: 978-3-642-14024-2
  • 41. Bischoff A, Eibisch M, Fuchs B, Süß R, Schürenberg M, Suckau D, Schiller J.A simple TLC/MALDI Method to monitor Oxidation Products of Phosphatidylcholines and -ethanolamines. Acta Chromatogr. 23 (2011) 365-375.
  • 40. Jakop U, Fuchs B, Süß R, Wibbelt G, Braun B, Müller K, Schiller, J. The solubilisation of boar sperm membranes by different detergents - a microscopic, MALDI TOF MS, 31P NMR and PAGE study on membrane lysis, extraction efficiency, lipid and protein composition. Lipids Health Dis. 8 (2009) 49.
  • 39. Fuchs B, Bischoff A, Süß R, Teuber K, Schürenberg M, Suckau D, Schiller J. Phosphatidylcholines and -ethanolamines can be easily mistaken in phospholipid mixtures: A negative ion MALDITOF MS study with 9-aminoacridine as matrix and egg yolk as selected example. Anal. Bioanal. Chem. 395 (2009) 2479-2487.
  • 38. Schober, C., Schiller, J., Pinker, F., Hengstler, J.G., Fuchs, B. Lysophosphatidylethanolamine is – in contrast to –choline - generated under in vivo conditions exclusively by phospholipase A2 but not by hypochlorous acid. Biorg. Chem. 37 (2009) 202-210.
  • 37. Fuchs, B., Schiller, J.pan>Recent developments of useful MALDI matrices for the mass spectrometric characterization of apolar compounds. Curr. Org. Chem. 13 (2009) 1664-1681.
  • 36. Fuchs, B., Nimptsch, A., Süß, R., Schiller, J. Capabilities and drawbacks of phospholipid analysis by MALDI-TOF mass spectrometry. In: Armstrong, D. (Ed.) "Lipidomics. Volume 1: Methods and Protocols" (Series: Methods in Molecular Biology. Vol. 579). Springer, New York Dordrecht Heidelberg London (2009) pp. 103-125. ISBN: 978-1-60761-321-3
  • 35. Fuchs, B., Bondzio, A., Wagner, U., Schiller, J. Phospholipid compositions of sera and synovial fluids from dog, human, and horse: A comparison by 31P NMR and MALDI-TOF MS. J. Anim. Physiol. Anim. Nutr. (Berl.) 93 (2009) 410-422.
  • 34. Leßig, J., Fuchs, B. Plasmalogens in biological systems: Their role in oxidative processes in biological membranes, their contribution to pathological processes and aging and plasmalogen analysis. Curr. Medic. Chem. 16 (2009) 2021-2041.
  • 33. Jaskolla, T., Fuchs, B., Karas, M., Schiller, J. The new matrix 4-chloro-α-cyanocinnamic acid allows the detection of phosphatidylethanolamine chloramines by MALDI TOF mass spectrometry. J. Am. Soc. Mass Spectrom. 20 (2009) 867-874.
  • 32. Fuchs, B., Süß, R., Nimptsch, A., Schiller, J. Matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) directly combined with thin-layer chromatography (TLC) - A review of the current state. Chromatographia 69 (2009) S95-S105.
  • 31. Fuchs, B., Schiller, J. Lysophospholipids: Their generation, physiological role and detection. Are they important disease markers? Mini-Rev. Med. Chem. 9 (2009) 368-378.
  • 30. Fuchs, B., Schiller, J., Süß, R., Nimptsch, A., Schürenberg, M., Suckau, D. Capabilities and drawbacks of combined matrix assisted laser desorption / ionization time-of-flight mass spectrometry (MALDI-TOF MS) and high-performance thin-layer chromatography (HPTLC): Analysis of egg yolk lipids. J. Planar Chromatogr. 22 (2009) 35-42.
  • 29. Fuchs, B., Schiller, J. Application of MALDI-TOF Mass Spectrometry in Lipidomics. Eur. J. Lipid Sci. Technol. 111 (2009) 83-98.
  • 28. Fuchs, B., Jakop, U., Göritz, F., Hermes, R., Hildebrandt, T., Schiller, J., Müller, K. MALDI-TOF "fingerprint" phospholipid mass spectra allow the differentiation between ruminantia and feloideae spermatozoa. Theriogenology 71 (2009) 568-575.
  • 27. Nimptsch, A., Schibur, S., Schnabelrauch, M., Fuchs, B., Huster, D., Schiller, J. Characterization of the quantitative relationship between signal-to-noise (S/N) ratio and sample amount on-target by MALDI-TOF MS: Determination of chondroitin sulfate subsequent to enzymatic digestion. Anal. Chim. Acta 635 (2009) 175-182.
  • 26. Fuchs, B., Schiller, J. MALDI-TOF MS analysis of lipids from cells, tissues and body fluids. In: Quinn, P.J., Wang, X. (Eds.) "Lipids in Health and Disease". Series: Subcellular Biochemistry. Volume 48. Springer. Berlin (2008) pp. 541-565. ISBN: 978-1-4020-8830-8
  • 25. Fuchs, B., Arnold, K., Schiller, J.Mass spectrometry of biological molecules. In: Meyers, R.A. (Ed.) "Encyclopedia of Analytical Chemistry", John Wiley & Sons Ltd., Chichester (2008) pp. 1-39. ISBN: 978-0-471-97670-7
  • 24. Fuchs, B., Nimptsch, A., Süß, R., Schiller, J. The analysis of brain lipids by a directly coupled MALDI/TLC approach. J. AOAC Int. 91 (2008) 1227-1236.
  • 23. Fuchs, B., Schiller, J., Süß, R., Zscharnack, M., Bader, A., Müller, P., Schürenberg, M., Becker, M., Suckau, D.Analysis of stem cell lipids by offline HPTLC-MALDI-TOF MS. Anal. Bioanal. Chem. 392 (2008) 849–860.
  • 22. Fuchs, B., Süß, R., Nimptsch, A., Schiller, J. MALDI-TOF MS: Mehr als Proteinanalytik! BIOforum 5 (2008) 33-35.
  • 21. Fuchs, B., Schober, C., Richter, G., Nimptsch, A., Süß, R., Schiller, J.The Reactions between HOCl and differently saturated phospholipids: Physiological relevance, products and methods of evaluation. Mini-Rev. Org. Chem. 5 (2008) 254-261.
  • 20. Richter, G., Schober, C., Süß, R., Fuchs, B., Müller, M., Schiller, J. The Reaction between Phosphatidylethanolamines and HOCl investigated by TLC: Fading of the Dye Primuline is induced by Dichloramines. Journal of Chromatography B 867 (2008) 233-237.
  • 19. Richter, G., Schober, C., Süß, R., Fuchs, B., Birkemeyer, C., Schiller, J. Comparison of the positive and negative ion ESI and MALDI-TOF mass spectra of the reaction products of phosphatidylethanolamines and HOCl. Anal. Biochem. 376 (2008) 157-159.
  • 18. Fuchs, B., Schiller, J., Cross, M.Apoptosis-associated changes in the glycerophospholipid composition of hematopoietic progenitor cells monitored by 31P-NMR spectroscopy and MALDI-TOF mass spectrometry. Chem. Phys. Lipids 150 (2007) 229-238.
  • 17. Fuchs, B., Müller, K., Göritz, F., Blottner, S., Schiller, J. Characteristic oxidation products of choline plasmalogens are detectable in cattle and roe deer spermatozoa by MALDI-TOF mass spectrometry. Lipids 42 (2007) 991-998.
  • 16. Fuchs, B., Schiller, J., Süß, R., Schürenberg, M., Suckau, D. A direct and simple Coupling Method between Matrix-assisted Laser Desorption and Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) and Thin-Layer Chromatography (TLC) for the Analysis of Phospholipids from Egg Yolk. Anal. Bioanal. Chem. 389 (2007) 827-834.
  • 15. Schiller, J., Müller, M., Fuchs, B., Arnold, K., Huster, D. 31P NMR spectroscopy of phospholipids: From micelles to membranes. Curr. Anal. Chem. 3 (2007) 283-301.
  • 14. Leßig, J., Schiller, J., Arnhold, J., Fuchs, B.Hypochlorous acid-mediated generation of glycerophosphocholine from unsaturated plasmalogen glycerophosphocholine lipids. J. Lipid Res. 48 (2007) 1316-1324.
  • 13. Fuchs, B., Schober, C., Richter, G., Süß, R., Schiller, J. MALDI-TOF MS of Phosphatidylethanolamines: Different Adducts cause different Post Source Decay (PSD) Fragment Ion Spectra. J. Biochem. Biophys. Methods 70 (2007) 689-692.
  • 12. Schiller, J., Süß, R., Fuchs, B., Müller, M., Petkovic, M., Zschörnig, O., Waschipky, H. The suitability of different DHB isomers as matrices for the MALDI-TOF MS analysis of phospholipids: Which isomer for what purpose? Eur. J. Biophys. 36 (2007) 517-527.
  • 11. Schiller, J., Süß, R., Fuchs, B., Müller, M., Zschörnig, O., Arnold, K. MALDI-TOF MS in lipidomics. Frontiers in Bioscience 12 (2007) 2568-2579.
  • 10. Fuchs B. , Schiller J. , Arnold K. Sodium cholate: an ideal detergent to obtain highly resolved 31P NMR spectra of phospholipids. Chim. Oggi Suppl. "Household & Personal Care Today" (2006) 28-31.
  • 9. Schiller, J., Fuchs, B., Arnold, K.The molecular organization of polymers of cartilage in health and disease. Curr. Org. Chem. 10 (2006) 1171-1789.
  • 8. Schiller, J., Süß, R., Fuchs, B., Müller, M., Zschörnig, O., Arnold, K. Recent Applications of MALDI-TOF Mass Spectrometry and 31P NMR Spectroscopy in Phospholipid Research. Future Lipidol. 1 (2006) 115-125.
  • 7. Fuchs, B., Schiller, J., Wagner, U., Häntzschel, H., Arnold, K. The phosphatidylcholine/lysophosphatidylcholine ratio in human plasma is an indicator of the severity of rheumatoid arthritis: Investigations by 31P NMR and MALDI-TOF MS. Clin. Biochem. 38 (2005) 925-933.
  • 6. Petkovic, M., Schiller, J., Müller, J., Leßig, J., Fuchs, B., Müller, M., Arnhold, J. Applications of mass spectrometric methods for investigations of kinetics of phospholipases. In "Recent Research Developments in Lipids". Editor S.G. Pandalai. Transworld Research Network, Trivandrum (2005) pp. 53-94.ISBN 81-7895-165-7
  • 5. Schiller, J., Süß, R., Arnhold, J., Fuchs, B., Leßig, J., Müller, M., Petkovic, M., Spalteholz, H., Zschörnig, O., Arnold, K.Matrix-Assisted Laser Desorption and Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry in Lipid and Phospholipid Research. Prog. Lipid Res. 43 (2004) 449-488.
  • 4. Schiller, J., Huster, D., Fuchs, B., Naji, L., Kaufmann, J., Arnold, K. Evaluation of cartilage composition and degradation by high resolution magic angle spinning nuclear magnetic resonance. In: De Ceuninck, F., Pastoureau, P., Sabatini, M. "Osteoarthritis: Methods and Protocols". Humana Press, Totowa (2004) pp. 267-286. ISBN: 1-59259-821-8.
  • 3. Schiller, J., Fuchs, B., Huster, D., Naji, L., Arnold, K. Structural properties of normal and diseased cartilage from the view of biophysical chemistry. Curr. Topics Biochem. Res. 5 (2003) 43-63.
  • 2. Schiller, J., Fuchs, B., Arnhold, J., Arnold, K.Contribution of reactive oxygen species to cartilage degradation in rheumatic diseases: Molecular pathways, diagnosis and potential therapeutic strategies. Curr. Medic. Chem. 10 (2003) 2123-2145.
  • 1. Schiller, J., Süß, R., Fuchs, B., Müller, M., Zschörnig, O., Arnold, K.Combined Application of TLC and Matrix-Assisted Laser Desorption and Ionisation Time-of-Flight Mass Spectrometry (MALDI-TOF MS) to Phospholipid Analysis of Brain. Chromatographia 57 (2003) 297-302.