|
Δημοσιεύσεις 2004 - 2006
- V. Wascholowski, A. Giannis,
Angew. Chem. Int. Ed., 2006, 45, 827-830.
"Sphingolactones: Selective and Irreversible Inhibitors of Neutral Sphingomyelinase"
- V. Sarli, A. Giannis,
ChemMedChem, 2006, 1, 293-298.
"Inhibitors of Mitotic Kinesins: Next-Generation Antimitotics"
- A. Schulze, A. Giannis,
Synthesis, 2006, 2, 257-260.
"Oxidation of Alcohols with Catalytic Amounts of IBX"
- A. Schulze, G. Pagona, A. Giannis,
Synth. Commun., 2006, 36, 1147-1156.
"Oxone/Sodium Chloride: A Simple and Efficient Catalytic System for the Oxidation of Alcohols to Symmetric Esters and Ketones"
- M. Biel, P. Deck, A. Giannis, H. Waldmann,
Chem. Eur. J., 2006, 12, 4121-4143.
"Synthesis and Evaluation of Acyl Protein Thioesterase 1 (APT1) Inhibitors"
- M. Liu, R. Aneja, C. Liu, L. Sun, J. Gao, H. Wang, J.T. Dong, V. Sarli, A. Giannis, HC Joshi, J. Zhou,
J. Biol. Chem., 2006, 281, 18090 - 18097.
"Inhibition of the mitotic kinesin Eg5 upregulates Hsp70 through the PI3K/Akt pathway in multiple myeloma cells"
- V. Wascholowski, A. Giannis, E. N. Pitsinos,
ChemMedChem, 2006, 1, 718-721.
"Influence of the Side Chain of Scyphostatin on the Mode of Inhibition of Neutral Sphingomyelinase"
- C. M. Thiele, A. Marx, R. Berger, J. Fischer, M. Biel, A. Giannis,
Angew. Chem. Int. Ed., 2006, 45, 4455-4460.
"Determination of the Relative Configuration of a Five-Membered Lactone from Residual Dipolar Couplings"
- J. Hoffmann, Y. Feng, F. vom Hagen, A. Hillenbrand, J. Lin, R. Erber, P. Vajkoczy, E. Gourzoulidou, H. Waldmann, A. Giannis, H. Wolburg, M. Shani, V.
Jaeger, H. A. Weich, K. T. Preissner, S. Hoffmann, U. Deutsch and H.-P. Hammes,
FASEB J., 2005, Published online October 7.
"Endothelial survival factors and spatial completion, but not pericyte coverage of retinal capillaries, determine vessel plasticity"
- M. Biel, V. Wascholowski, A. Giannis,
Angew. Chem. Int. Ed., 2005, 44, 3186-3216.
"Epigenetics - An Epicenter of Gene Regulation: Histones and Histone-Modifying Enzymes"
- M. Gartner, N. Sunder-Plassmann, J. Seiler, M. Utz, I. Vernos, T. Surrey, A. Giannis,
ChemBioChem, 2005, 6, 1173-1177.
"Development and Biological Evaluation of Potent and Specific Inhibitors of Mitotic Kinesin Eg5"
- R. Mazitschek, A. Huwe, A. Giannis,
Org. Biomol. Chem., 2005, 3, 2150-2154.
"Synthesis and Biological Evaluation of Novel Fumagillin and Ovalicin Analogues"
- P. Deck, D. Pendzialek, M. Biel, M. Wagner, B. Popkirova, B. Ludolph, G. Kragol, J. Kuhlmann, A. Giannis, H. Waldmann,
Angew. Chem. Int. Ed., 2005, 44, 4975-4980.
"Development and Biological Evaluation of Acyl Protein Thioesterase 1 (APT1) Inhibitors"
- E. Gourzoulidou, M. Carpintero, P. Baumhof, A. Giannis, H. Waldmann,
ChemBioChem, 2005, 6, 527-531.
"Inhibition of Angiogenesis-Relevant Receptor Tyrosine Kinases by Sulindac Analogues"
- M. Anderluh, J. Cesar, P. Stefanic, D. Kikelj, D. Janes, J. Murn, K. Nadrah, M. Tominc, E. Addicks, A. Giannis, M. Stegnar, M. S. Dolenc,
Eur. J. Med. Chem, 2005, 40, 25-49.
"Design and synthesis of novel platelet fibrinogen receptor antagonists with 2H-1,4-benzoxazine-3(4H)-one scaffold. A systematic study"
- M. Gartner, T. Müller, J. C. Simon, A. Giannis, J. P. Sleeman,
ChemBioChem, 2005, 6, 171-177.
"Aristoforin, a Novel Stable Derivative of Hyperforin, Is a Potent Anticancer Agent"
- V. Sarli, S. Huemmer, N. Sunder-Plassmann, T. U. Mayer, A. Giannis,
ChemBioChem, 2005, 6, 2005-2013.
"Synthesis and Biological Evaluation of Novel Eg5 Inhibitors"
- N. Sunder-Plassmann, V. Sarli, M. Gartner, M. Utz, J. Seiler, S. Huemmer, T. U. Mayer, T. Surrey, A. Giannis,
Bioorg. Med. Chem., 2005, 13, 6094-6111.
"Synthesis and Biological Evaluation of New Tetraheydro-b-carbolines as Inhibitors of the Mitotic Kinesine Eg5"
- M. Biel, V. Wascholowski, A. Giannis,
Angew. Chem. Int. Ed., 2004, 43, 6414-6416.
"A Fatal Affair: The Ubiquitinylation of Proteins"
- N. Sunder-Plassmann, A. Giannis,
ChemBioChem, 2004, 5, 1635-1637.
"Novel Activators of the Tumour Suppressor p53"
- V. Kirkin, W. Thiele, P. Baumann, R. Mazitschek, K. Rohde, G. Fellbrich, H. Weich, J. Waltenberger, A. Giannis, J. P. Sleeman,
Int. J. Cancer, 2004, 112, 986-993.
"MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo"
- S. Al-Rawy, S. Hinderlich, W. Reutter, A. Giannis,
Angew. Chem. Int. Ed., 2004, 43, 4366-4370.
"Synthesis and Biochemical Properties of Reversible Inhibitors of UDP-NAcetylglucosamine 2-Epimerase"
- C. Gey, A. Giannis,
Angew. Chem. Int. Ed., 2004, 43, 3998-4000.
"Small Molecules, Big Plans - Can Low-Molecular-Weight Compounds Control Human Regeneration?"
- R. Mazitschek, A. Giannis,
Curr. Opin. Chem. Biol., 2004, 8, 432-441.
"Inhibitors of angiogenesis and cancer-related receptor tyrosine kinases"
- M. Biel, A. Kretsovali, E. Karatzali, J. Papamatheakis, A. Giannis,
Angew. Chem. Int. Ed., 2004, 43, 3974-3976.
"Design, Synthesis, and Biological Evaluation of a Small-Molecule Inhibitor of the Histone Acetyltransferase Gcn5"
- A. S. Unsoeld, B. Junker, R. Mazitschek, G. Martin, L. L. Hansen, A. Giannis, H. T. Agostini,
Molecular Vision, 2004, 10, 468-475.
"Local injection of receptor tyrosine kinase inhibitor MAE 87 reduces retinal neovascularization in mice"
- P. Stefanic, Z. Simoncic, M. Breznik, J. Plavec, M. Anderluh, E. Addicks, A. Giannis, D. Kikelj,
Org. Biomol. Chem., 2004, 2, 1511-1517.
"Conformationally tailored N-[(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl)carbonyl]proline templates as molecular tools for the design of peptidomimetics. Design and synthesis of fibrinogen receptor antagonists"
- A. Schulze, A. Giannis,
Adv. Synth. Catal., 2004, 346, 252-256.
"IBX-Mediated Conversion of Primary Alcohols and Aldehydes to N-Hydroxysuccinimide Esters"
- C. Rosenbaum, P. Baumhof, R. Mazitschek, O. Müller, A. Giannis, H. Waldmann,
Angew. Chem. Int. Ed., 2004, 43, 224-228.
"Synthesis and Biological Evaluation of an Indomethacin Library Reveals a New Class of Angiogenesis-Related Kinase Inhibitors"
|
|
