Results: Publications "Spindle Dynamics"

1. Joint Publications
   
   • A. Christodoulou, C.W. Lederer, T. Surrey, I. Vernos, N. Santama J. Cell Sci., 2006, 119, 2035-2047.
     "Motor protein KIFC5A interacts with Nubp1 and Nubp2 and is implicated in the regulation of centrosome duplication"
   • V. Sarli, S. Huemmer, N. Sunder-Plassmann, T. U. Mayer, A. Giannis, ChemBioChem, 2005, 6, 2005-2013.
     "Synthesis and Biological Evaluation of Novel Eg5 Inhibitors"
   • N. Sunder-Plassmann, V. Sarli, M. Gartner, M. Utz, J. Seiler, S. Huemmer, T. U. Mayer, T. Surrey, A. Giannis, Bioorg. Med. Chem., 2005, 13, 6094-6111.
     "Synthesis and Biological Evaluation of New Tetraheydro-b-carbolines as Inhibitors of the Mitotic Kinesine Eg5"
   • M. Gartner, N. Sunder-Plassmann, J. Seiler, M. Utz, I. Vernos, T. Surrey, A. Giannis, ChemBioChem, 2005, 6, 1173-1177.
     "Development and Biological Evaluation of Potent and Specific Inhibitors of Mitotic Kinesin Eg5"
2. Additional Publications directy resulting from the project
   
   • A. Olichon, T. Surrey, J. Biol. Chem. 2007, 282, 36314-20.
     "Selection of genetically encoded fluorescent single domain antibodies engineered for efficient expression in Escherichia coli."
   • J. Espeut, A. Gaussen, P. Bieling, V. Morin, S. Prieto, D. Fesquet, T. Surrey, A. Abrieu, Mol. Cell, in press.
     "Phosphorylation relieves autoinhibition of the kinetochore motor Cenp-E."
   • C. Müller, D. Gross, V. Sarli, M. Gartner, A. Giannis, G. Bernhardt, A. Buschauer, Cancer Chemother Pharmacol, 2007, 59, 157-164.
     "Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells."
   • A. Khmelinskii, C. Lawrence, J. Roostalu, E. Schiebel, J. Cell Biol. 2007, 177, 981-993.
     "Cdc14-regulated midzone assembly controls anaphase B."
   • V. Sarli*, A. Giannis, accepted for the Book, "Checkpoint Responses and Cancer Therapy", Humana Press 2007.
     "Kinesin motor inhibitors as effective anti-cancer drugs."
   • A. Khmelinskii*, C. Lawrence, J. Roostalu*, E. Schiebel J. Cell Biol.in press.
     "Regulation of Ase1 by Cdc14 controls anaphase spindle extension."
   • A. Csikász-Nagy, O. Kapuy, B. Györffy, J.J. Tyson, B. Novák, Current Genetics 2007, 51, 245-255.
     "Modeling the Septation Initiation Network (SIN) in fission yeast cells."
   • A. Olichon*, D. Schweizer, S. Muyldermans, A. de Marco, BMC Biotechnol. 2007, 7, 7. "Heating as a rapid purification method for recovering correctly-folded thermotolerant VH and VHH domains."
   • E. Queralt, C. Lehane, B. Novák, F. Uhlmann, Cell 2006, 125,719-732.
     "Downregulation of PP2A^Cdc55 phosphatase by separase initiates mitotic exit in budding yeast."
   • E. Karsenti, F. Nedelec, T. Surrey, Nat. Cell Biol. 2006, 8, 1204-11.
     "Modelling microtubule patterns."
   • M. Liu, R. Aneja, C. Liu, L. Sun, J. Gao, H. Wang, J.T. Dong, V. Sarli, A. Giannis, HC Joshi, J. Zhou,
     J. Biol. Chem., 2006, 281, 18090 - 18097.
     "Inhibition of the mitotic kinesin Eg5 upregulates Hsp70 through the PI3K/Akt pathway in multiple myeloma cells."
   • J. Pearson, S. Godinho, A. Tavares, DM. Glover, Exp. Cell Res. 2006, 312,770 - 781.
     "Heterologous expression of mammalian Plk1 in Drosophila reveals divergence from Polo during late mitosis."
   • V. Sarli, A. Giannis, ChemMedChem 2006, 1, 293-298.
     "Inhibitors of Mitotic Kinesins: Next-Generation Antimitotics"