Tamara Tal
Using zebrafish larvae to understand chemical phenotypes, mechanisms, and the microbiome
Brain Dynamics Graduate School is happy to announce a new online talk in our Seminar Series:
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Prof. Dr. Tamara Tal
Department of Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig
"Using zebrafish larvae to understand chemical phenotypes, mechanisms, and the microbiome"
Zoom Meeting (https://uni-leipzig.zoom.us/j/69538354959?pwd=TC9wZFROWlZtRzJKMEN1cTJTU0JGdz09
Meeting ID: 695 3835 4959
Passcode: 658422)
1st July 2022, 12:00
Abstract:
We live in a polluted world. From a chemical safety perspective, zebrafish are increasingly used as an alternative test system for hazard identification and chemical prioritization. The model system is also well-placed to reveal mechanisms by which xenobiotics cause adverse outcomes. Prof. Dr. Tal will discuss the scope of the problem regarding chemicals in the environment and give an overview of the strategies her group uses to tackle the issue, including the development of new approach methods for learning and memory effects, demonstration of causality between chemical exposure, molecular targets, and neurotoxicological adverse outcomes, and the evaluation of toxicokinetic and toxicodynamic interactions between xenobiotics and the microbiome-gut-brain axis.
Short Bio:
Prof. Dr. Tamara Tal leads the Molecular Toxicology Group at the Helmholtz Centre for Environmental Health Research – UFZ. Since 2021, she also holds a professorship in Integrated Systems Toxicology in the Medical Faculty at University Leipzig. Prior to joining the UFZ in 2019, Tamara was a Principal Investigator at the United States Environmental Protection Agency (EPA). Tamara completed postdoctoral fellowships in the labs of Dr. Robyn Tanguay (Oregon State University) and Dr. Stephanie Padilla (EPA) and earned a doctorate in toxicology from the University of North Carolina at Chapel Hill under the mentorship of Dr. James Samet.