Profile

Professional career

• 06/2009 - 10/2009
  Visiting Professor at Vanderbilt University, Nashville, TN, USA
• since 07/2000
  Member of the Faculty of Chemistry and Mineralogy, Leipzig University
• since 08/1999
  Full Professor (C4) of Bioorganic Chemistry and Biochemistry, Faculty of Life Sciences at Leipzig University
• 01/1997 - 07/1999
  Assistant Professor, Pharmaceutical Biochemistry, ETH Zürich, Department of Applied Chemistry, Switzerland
• 01/1992 - 12/1992
  Research Fellow at Rigshospitalet, Copenhagen, Denmark (T. W. Schwartz)
• 07/1990 - 12/1991
  Postdoctoral Fellow, ETH Zürich, Laboratory of Biochemistry, Switzerland (E. Carafoli)
• 01/1988 - 10/1988
  Research Stay at Scripps Clinic & Research Foundation, La Jolla, USA (R. A. Houghten)

Education

• 11/1989 - 10/1995
  Habilitation and venia legendi in Biochemistry, University of Tübingen
• 11/1986 - 10/1989
  Dissertation in Organic Chemistry, University of Tübingen
• 10/1982 - 10/1990
  Studies and Final Degree in Biology, University of Tübingen
• 10/1980 - 10/1986
  Studies and Final Degree in Organic Chemistry, University of Tübingen

Panel Memberships

• since 07/2021
  Member of the DFG Senate
• since 01/2021
  Member of the Academy of Science, Göttingen
• since 01/2020
  Speaker of the CRC 1423: Structural Dynamics of GPCR Activation and Signaling (DFG)
• 01/2019 - 03/2021
  President of the German Society for Biochemistry and Molecular Biology (GBM)
• 01/2017 - 01/2023
  Member of the Board of the German Society for Biochemistry and Molecular Biology (GBM); Vice President 2017-2019 and 2021-2023
• 01/2015 - 01/2023
  Member of the Senate Board of Evaluation of the Leibnitz Foundation
• since 01/2013
  Member of the Board of the CRC 1052: Obesity Mechanisms (DFG)
• since 01/2012
  Member of the University Council (Hochschulrat) Leipzig, since 2018 vice speaker
• since 01/2012
  Member of the German National Academy of Science, Leopoldina
• 01/2012 - 12/2018
  Member of the German Council of Science and Humanities(Wissenschaftsrat)
• 01/2011 - 03/2021
  Member of the University Council (Universitätsrat) University of Stuttgart-Hohenheim, speaker 2018-2021
• 07/2009 - 12/2021
  Member of the Board of the CRC-TR67 and Chair of the Graduate Programm “Matrix Engineering”
• since 01/2012
  Member of the German National Academy of Science, Leopoldina
• since 01/2009
  Member of the Saxonian Academy of Sciences
• since 01/2009
  Member of the Advisory Board of the Mercator Foundation
• since 01/2008
  Member of the „Kuratorium des Fonds der Chemischen Industrie“ (FCI)
• since 01/2013
  Coordinator of the Leipzig-Vanderbilt Max Kade Foundation Program to support international exchange with Vanderbilt University, Nashville, TN, USA
• 01/2002 - 12/2012
  Speaker of the CRC 610 „Variation in Protein Conformation: Cell biological and Pathological Relevance“ (DFG)

Her major research fields are structure-activity-relationships of peptide and protein ligands activating G protein coupled receptors and protein modification to study molecular interactions. A tight connection of chemical methods, bioorganic synthesis and molecular biology tools, including cloning, receptor mutagenesis, protein expression and cell biochemistry is applied. Whereas in the first field, her interests go towards medicinal chemistry, identification of novel targets and novel therapeutic concepts e. g. in the field of cancer and obesity, the second field is related to biomaterials, novel approaches to modify proteins and concepts for improved drug delivery.

• SFB 1423: Structural Dynamics of GPCR Activation and Signaling

  Beck-Sickinger, Annette

  Duration: 01/2020 – ongoing

  Funded by: DFG Deutsche Forschungsgemeinschaft

  Involved organisational units of Leipzig University: SFB 1423: Strukturelle Dynamik der GPCR-Aktivierung und Signaltransduktion; Medizinische Fakultät und Universitätsklinikum AöR; Bioinformatik; Institut für Biochemie; Biochemie/Bioorganische Chemie; Pharmazeutische Chemie; Biotechnologisch-Biomedizinisches Zentrum; Interdisziplinäres Zentrum für Bioinformatik (IZBI); Rudolf-Schönheimer-Institut für Biochemie; Lehrstuhl für Molekulare Biochemie (Medizin); Rudolf-Boehm-Institut für Pharmakologie und Toxikologie; Institut für Medizinische Physik und Biophysik; Synthetische Proteinbiochemie
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• SFB 1052/A03: Targeting of central peptide receptors via nasal ligand application to modulate food intake

  Beck-Sickinger, Annette

  Duration: 07/2021 – 12/2024

  Funded by: DFG Deutsche Forschungsgemeinschaft

  Involved organisational units of Leipzig University: Biochemie/Bioorganische Chemie; Medizinische Fakultät und Universitätsklinikum AöR; SFB 1052: Mechanismen der Adipositas
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• Structure Elucidation of the Neuropeptide Y5 Receptor- Relevant in Food intake and Cancer

  Beck-Sickinger, Annette

  Duration: 05/2022 – 04/2025

  Funded by: DFG Deutsche Forschungsgemeinschaft

  Involved organisational units of Leipzig University: Biochemie/Bioorganische Chemie
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more projects

• Andere herausragende Auszeichnungen: IUPAC Award: Distinguished Women in Chemistry or Chemical Engineering

  Beck-Sickinger, Annette (Biochemie/Bioorganische Chemie)

  awarded in 2023.
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• Andere herausragende Auszeichnungen: Richard-Willstätter-Award for Chemical Biology

  Beck-Sickinger, Annette (Biochemie/Bioorganische Chemie)

  awarded in 2023.
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• Andere Ehrungen: Member of the Academy of Sciences, Göttingen

  Beck-Sickinger, Annette (Biochemie/Bioorganische Chemie)

  awarded in 2021.
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• Andere herausragende Auszeichnungen: Chemistry Europe Fellow Award

  Beck-Sickinger, Annette (Biochemie/Bioorganische Chemie)

  awarded in 2019.
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• Andere herausragende Auszeichnungen: Du Vigneaud Award

  Beck-Sickinger, Annette (Biochemie/Bioorganische Chemie)

  awarded in 2019 by American Peptide Society.
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more awards

• Biochemie/Bioorganische Chemie; Biotechnologisch-Biomedizinisches Zentrum (BBZ)

  Projet émergent TRAIL INNOVATHER

  Start Date of Collaboration: 01/10/2017

  Ended on: 30/09/2020

  Involved persons: Beck-Sickinger, Annette; Morgat, Clement
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• Biochemie/Bioorganische Chemie; Institut für Biochemie; Biotechnologisch-Biomedizinisches Zentrum (BBZ)

  Gastrointestinal peptides in obesity

  Start Date of Collaboration: 01/01/2015

  External participating organisations: King's College London (London, United Kingdom); University of Copenhagen (Copenhagen, Denmark)

  Involved persons: Beck-Sickinger, Annette; Cox, H. M.; Schwartz, Thue W.
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• Biochemie/Bioorganische Chemie; Institut für Biochemie; Biotechnologisch-Biomedizinisches Zentrum (BBZ)

  Vanderbilt-Leipzig Collaboration: International Student and Research Exchange Programme

  Start Date of Collaboration: 01/01/2009

  External participating organisations: Vanderbilt University (Nashville, United States)

  Involved persons: Beck-Sickinger, Annette; Meiler, Jens; Albrecht, Anett
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• Biochemie/Bioorganische Chemie; Institut für Biochemie; Biotechnologisch-Biomedizinisches Zentrum (BBZ)

  GPCR/arrestin interaction

  External participating organisations: Vanderbilt University (Nashville, United States)

  Involved persons: Beck-Sickinger, Annette; Gurevich, Vsevolod V.
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• Biochemie/Bioorganische Chemie; Institut für Biochemie; Biotechnologisch-Biomedizinisches Zentrum (BBZ)

  Small Molecule Probes to investigate Structure and Funktion of Y-Receptors

  External participating organisations: Vanderbilt University (Nashville, United States)

  Involved persons: Beck-Sickinger, Annette; Meiler, Jens
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more cooperations

• Internationale Tagung

  4GPCRnet 2022

  Biochemie/Bioorganische Chemie; Universität Leipzig; Medizinische Fakultät und Universitätsklinikum AöR

  Event Organiser: Beck-Sickinger, Annette; Bock, Andreas; Liebscher, Ines; Albrecht, Anett

  26/09/2022 – 29/09/2022
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• Internationale Tagung

  34. Europäisches und 8. internationales Peptidsymposium

  Biochemie/Bioorganische Chemie; Institut für Biochemie; Biotechnologisch-Biomedizinisches Zentrum (BBZ)

  Event Organiser: Beck-Sickinger, Annette; Albrecht, Anett

  04/09/2016 – 09/09/2016
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• Internationale Tagung

  11. Internationales NPY-PYY-PP Symposium

  Biochemie/Bioorganische Chemie; Institut für Biochemie; Biotechnologisch-Biomedizinisches Zentrum (BBZ)

  Event Organiser: Beck-Sickinger, Annette; Albrecht, Anett

  22/08/2015 – 26/08/2015
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• Konferenz

  13th Akabori Conference 2010. Japanese-German Symposium on Peptide Science

  Biochemie/Bioorganische Chemie

  Event Organiser: Beck-Sickinger, Annette

  10/09/2010 – 14/09/2010
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more events

• Modul "Receptor Biochemistry and Signal Transduction"

• Modul "Protein Chemistry/ Enzymology"

• Modul "Bioorganic Chemistry"

• Modul "Fundamentals of Biochemistry"

• Journalclub: Discussion of current biochemical publications

• Modul "Scientific work and theoretical course"