Profile
Abstract
Although the halogenation of organic molecules is one of the most widespread techniques for the functionalization of substrates, efficient catalytic methods for the selective installation of halogen atoms are rare. Our research program therefore addresses the long-standing problem of catalytic halogenation. Nature has developed different strategies to catalyze these types of reactions with high chemo-, regio, and stereospecificity. By exploring and emulating Nature’s concept, new catalysts are elaborated, which allow for the development of mild, generally applicable, and selective catalytic methods for the formation of carbon,halogen bonds, thus adding a particularly advantageous tool to the arsenal of methods in modern synthesis. With the application of these catalysts, novel compound classes with unique structures and potent biological activities are easily accessed, expanding the boundaries of chemical space.
Professional career
- since 01/2020
Professor for Organic Chemistry, Department of Chemistry and Mineralogy, University of Leipzig - 01/2018 - 12/2019
Heisenberg-Professor for Biomimetic Catalysis, Department of Chemistry and Catalysis Research Center, TU Munich - 06/2014 - 12/2017
Junior-Research-Group Leader, Department Chemie, TU Munich - 09/2010 - 05/2014
Junior-Research-Group Leader, Institute of Organic Chemistry, RWTH Aachen University - 05/2008 - 08/2010
Postdoctoral-Research Associate with Prof. Dr. P. S. Baran, Scripps Research Institute
Education
- 03/2004 - 03/2008
PhD Thesis with Prof. Dr. Dr. h.c. mult. G. Bringmann, Institute of Organic Chemistry, University of Würzburg - 05/2003 - 02/2004
Diploma Thesis with Prof. Dr. Dr. h.c. G. Bringmann, Institute of Organic Chemistry, University of Würzburg
- Learning from natures's lessons: development of bioinspired catalysts for selective oxidative halogenations and their application for the creation of potent biomedical agentsGulder, TanjaDuration: 03/2017 - 06/2022Funded by: DFG Deutsche ForschungsgemeinschaftInvolved organisational units of Leipzig University: Naturstoffchemie
- Catalytic, Asymmetric Halogenations mediated by hypervalent IodanesGulder, TanjaDuration: 01/2017 - 08/2022Funded by: DFG Deutsche ForschungsgemeinschaftInvolved organisational units of Leipzig University: Naturstoffchemie
- Electrochemical xH labelling in microheterogenously structured solutionsGulder, TanjaDuration: 10/2021 - 03/2026Funded by: DFG Deutsche ForschungsgemeinschaftInvolved organisational units of Leipzig University: Naturstoffchemie
- Photochemical Polyene Cyclizations in Microheterogenous, Fluorinated EnvironmentsGulder, TanjaDuration: 07/2021 - 06/2025Funded by: DFG Deutsche ForschungsgemeinschaftInvolved organisational units of Leipzig University: Naturstoffchemie
- Stierli, D.; Eberle, M.; Lamberth, C.; Jacob, O.; Balmer, D.; Gulder, T.Quarternary α-cyanobenzylsulfonamides: A new subclass of CAA fungicides with excellent anti-Oomycetes activityBioorganic & Medicinal Chemistry. 2021. p. 115965
- Kiefl, G.; Gulder, T.α-Functionalization of Ketones via a Nitrogen Directed Oxidative UmpolungJournal of the American Chemical Society. 2020. 142 (49). pp. 20577-20582DOI: 10.1021/jacs.0c10700