Research at the BBZ  

Research at the BBZ

Scientific publications 2010

Ahsanullah; Rademann, J.
Cyclative cleavage of azido-peptidyl-phosphoranes delivers locked cis-triazolyl-cyclopeptides as privileged protein binders, Angew. Chem. 122 (2010), 5506–5510, Angew. Chem. Int. Ed. 49, 5378–5382

Beindorff, N.; Einspanier, A.
Luteotrophic effects of relaxin, chorionic gonadotrophin and FSH in common marmoset monkeys (Callithrix jacchus), Reproduction 139(5) (2010), 923–930

Bellmann-Sickert, K.; Beck-Sickinger, A.G.
Peptide Drugs to Target G-Protein Coupled Receptors, Trends Pharm. Sci.  31 (2010), 434–441

Böhlig, L.; Friedrich, M.; Engeland, K.
p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins, Nucleic Acids Research (2010), Epub ahead of print

Findeiß, S.; Schubert, C.; Stadler, P.F.; Bonas, U.
A novel family of plasmid-transferred anti-sense ncRNAs, RNA Biology 7 (2010), 120–124

Fischer, S.; Wiese, C.; Grosse; Maestrup, E.;  Hiller, A.; Deuther-Conrad, W.; Scheunemann, M.; Schepmann, D.; Steinbach, J.;  Wünsch, B.; Brust, P.
Synthesis, pharmacological activity and structure-affinity relationships of spirocyclic σ1 receptor ligands with a (2-fluoroethyl) residue in 3-position, Eur. J. Nucl. Med. Mol. (2010), Imaging

Fritsch, A.; Höckel, M.; Kiessling, T.; Nnetu, K.D.; Wetzel, F.; Zink, M.; Käs, J.A.
Are biomechanical changes necessary for tumour progression?, Nature Physics. 6(10) (2010), 730–732

Gebhardt, C.; Averbeck, M.; Diedenhofen, N.; Willenberg, A.; Anderegg, U.; Sleeman, J.P.; Simon, J.C.
Dermal hyaluronan is rapidly reduced by topical treatment with glucocorticoids, J. Invest. Dermatol. 130(1)n (2010), 141–149, ISSN 0022-202X

Giri, S.; Nieber, K.; Acikgoz, A.; Pavlica, S.; Keller, M.; Bader, A.
Telomerase activity and hepatic functions of rat embryonic liver progenitor cell in nanoscaffold-coated model bioreactor, Mol. Cell. Biochem. 336(1-2) (2010), 137–149, ISSN 0300-8177

Haas, S.; Jahnke, H.G.; Glass, M.; Azendorf, R.; Schmidt, S.; Robitzki, A.A.
Real-time monitoring of relaxation and contractility of smooth muscle cells on a novel biohybrid chip, Lab-On-Chip 10(21) (2010), 2965–2971

Halwachs, S.; Lakoma, C.; Gebhardt, R.; Schäfer, I.; Seibel, P.; Honscha, W.
Dioxin mediates downregulation of the reduced folate carrier transport activity via the arylhydrocarbon receptor signalling pathway, Toxicol. Appl. Pharmacol. 246(1-2) (2010), 100–106

Hanisch, K.; Sininen, H.; Alafuzoff, I.; Hoffmann, R.
Analysis of human Tau in cerebrospinal fluid, J. Proteome. Res. 9(3) (2010), 1476–1482

Hartung, M.; Loebe, F.; Herre, H.; Rahm, E.
Management of Evolving Semantic Grid Metadata Within a Collaborative Platform, Information Sciences 180(10) (2010), 1837–1849

Heretsch, P.; Rabe, S.; Giannis, A.
A Biomimetic Approach to C-nor-D-homo-Steroids, J. Am. Chem. Soc. 132(29) (2010), 9968–9969

Heretsch, P.; Tzagkaroulaki, L.; Giannis, A.
Modulators of the hedgehog signaling pathway, Bioorg. Med. Chem. 18(18) (2010), 6613–6624

Hofacker, I.L.; Flamm, C.; Heine, C.; Wolfinger, M.T..; Scheuermann, G.; Stadler, P.F.
BarMap: RNA folding on dynamics energy landscapes, RNA 16 (2010), 1308–1316

Jungke, P.; Ostrow, G.; Li, J.L..; Norton, S.; Nieber, K.; Kelber, O.; Butterweck, V.
Profiling of hypothalamic and hippocampal gene expression in chronically stressed rats treated with St. John´s wort extract (STW 3-VI) and fluoxetine, Psychopharmacology (2010), PMID 20924750

Khan, I.U.; Zwanziger, D.; Böhme, I.; Javed, M.; Naseer, H.; Hyder, S.W.; Beck-Sickinger, A.G.
Breast cancer diagnosis by neuropeptide Y analogues - first clinical approach, Angew. Chem. 49 (2010),

Kleinschek, M.A.; Müller, U.; Schütze, N.; Sabat, R.; Straubinger, R.K.; Blumenschein,W.M.; McClanahan, T.; Kastelein, R.A.; Alber, G.
Administration of IL-23 engages innate and adaptive immune mechanisms during fungal infection. Int. Immunol. 22(2010), 81

Krinke, D.; Jahnke, H.G.; Mack, T.G.A.; Hirche, A.; Striggow, F.; Robitzki, A.A.
A novel organotypic tauopathy model on a new microcavity chip for bioelectronic label-free and real time monitoring, Biosensors and Bioelectronics 26(1) (2010), 162–168

Kuettner, E.B.; Kettner, K.; Keim, A.; Svergun, D.I.; Volke, D.; Singer, D.; Hoffmann, R.; Muller, E.C.; Otto, A.; Kriegel, T.M.; Strater, N.
Crystal Structure of the Hexokinase KlHxk1 of Kluyveromyces lactis. A molecular basis to understand the control of yeast hexokinase functions via covalent modification and oligomerization, J. Biol. Chem. (2010), PMID: 20943665

Lu, Y.B.; Iandiev, I.; Hollborn, M.; Körber, N.; Ulbricht, E.; Hirrlinger, P.G.; Pannicke, T.; Wei, E.Q.; Bringmann, A.; Wolburg, H.; Wilhelmsson, U.; Pekny, M.; Wiedemann, P.; Reichenbach, A.; Käs, J.A.
Reactive glial cells: increased stiffness correlates with increased intermediate filament expression, FASEB. J. ,
Epub 2010

Marg, S.; Winkler, U.; Sestu, M.; Himmel, M.; Schönherr, M.; Bär, J.; Mann, A.; Moser, M.; Mierke, C.T.; Rottner, K.; Blessing, M.; Hirrlinger,  J.; Ziegler W.H.
The vinculin-DeltaIn20/21 mouse: characteristics of a constitutive, actin-binding deficient splice variant of vinculin, PLoS One 5(7) (2010), e11530

Maringka, M.; Giri, S.; Bader, A.
Preclinical characterization of primary porcine hepatocyte in a clinical relevant flat membrane bioreactor, Biomaterials 31(1) (2010), 156–172

Merkle, D.; Middendorf, M.; Wieske, N.
A Parameter-Adaptive Dynamice Programming Approach for Inferring Cophylogenies, BMC Bioinformatics 11(1) (2010), 60

Morawski, M.; Hartlage-Rübsamen, M.; Jäger, C.; Waniek, A.; Schilling, S.; Schwab, C.; McGeer, P.L.; Arendt, T.; Demuth, H.U.; Rossner, S.
Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer’s disease, Acta Neuropathol 120(2) (2010), 195–207, ISSN 0001-6322

Papadopoulos, P.; Heinze, P.; Finkelmann, H.; Kremer, F.
Electromechanical properties of smectic C* liquid crystal elastomers under shear, Macromolecules 43 (16) (2010), 6666-6670

Pacelli, C.; Latorre, D.; Cocco, T.; Capuano, F.; Kukat, C.; Seibel, P.; Villani, G.
Tight control of mitochondrial membrane potential by cytochrome c oxidase, Mitochondrion (2010), epub ahead of print

Perseke, M.; Bernhard, D.; Fritzsch, G.; Brümmer, F.; Stadler, P.F.; Schlegel, M.
Mitochondrial genome evolution in Ophiuroidea, Echinoidea, and Holothuroidea: Insights in phylogenetic relationships of Echinodermata, Molecular Phylogenetics and Evolution 56 (2010),  201–211

Räuber, C.; Berger, S.
13C-NMR detection of STD spectra, Magn. Reson. Chem. 48 (2010); 91-93

Reichenbach, A.; Derouiche, A.; Kirchhoff, F.
Morphology and dynamics of perisynaptic glia, Brain Res.Rev. 63(1-2) (2010), 11-25, ISSN 0165-0173

Singer, D.; Kuhlmann, J.; Muschket, M.; Hoffmann, R.
Separation of multiphosphorylated peptide isomers by hydrophilic interaction chromatography on an aminopropyl phase, Anal. Chem. 82 (2010), 6409–6414

Singer, D.; Zauner, T.; Genz, M.; Hoffmann, R.; Züchner, T.
Synthesis of pathological and nonpathological human exon 1 huntingtin, J. Pept. Sci. 16 (2010); 358–363

Stadlbauer, S.; Lönnecke, P.; Welzel, P.; Hey-Hawkins, E.
Bis-Carbaborane-Bridged Bis-Glycophosphonates as Boron-Rich Delivery Agents for BNCT, Europ.  J. Org. Chem. (2010), 3129-3139

Sträter, N.; Marek, S.; Kuettner, E.B.; Kloos, M.; Keim, A.; Brüser, A.; Kirchberger, J.; Schöneberg, T.
Molecular architecture and structural basis of allosteric regulation of eukaryotic phosphofructokinases, FASEB. J. 25(1) (2010), 89–98

Wehrhahn, J.; Kraft, R.; Harteneck, C.; Hauschildt, S.
Transient receptor potential melastatin 2 is required for lipopolysaccharide-induced cytokine production in human monocytes, J. Immunol. 184 (2010), 2386–2393

Wenzel, B.; Fischer, S.; Brust, P.; Steinbach, J.
Accessible silanol sites - beneficial for the RP-HPLC separation of constitutional and diastereomeric azaspirovesamicol isomers,  J. Chromatography A. 1217 (2010), 7884–7890

Ziepert, M.; Hasenclever, D.; Kuhnt, E.; Glass, B.; Schmitz, N.; Pfreundschuh, M.; Loeffler, M.
Standard International Prognostic Index Remains a Valid Predictor of Outcome for Patients With Aggressive CD20+ B-Cell Lymphoma in the Rituximab Era, Journal of Clinical Oncology 28(14) (2010), 2373–2380

last update: 06.02.2017 


Centre for Biotechnology and Biomedicine
Deutscher Platz 5
04103 Leipzig

Phone: +49 341 97-31300
Fax: +49 341 97-31309

Prof. Dr. Andrea A. Robitzki

Chief Executive Officer
Dr. Svenne Eichler