Forschung am BBZ  

Forschung am BBZ

Wissenschaftliche Veröffentlichungen 2011

Piehler D, Stenzel W, Grahnert A, Held J, Richter L, Köhler G, Richter T, Eschke M, Alber G, Müller U
Eosinophils contribute to IL-4 production and shape the T helper cytokine profile and inflammatory response in pulmonary cryptococcosis. Am J Pathol, Aug, 179(2) (2011) 733-744, Epub 2011 May 31

Morawski M, Brückner G, Jäger C, Seeger G, Matthews R, Arendt T
Involvement of perineuronal and perisynaptic extracellular matrix in Alzheimer's disease neuropathology. Brain Pathol  Nov 29 (2011)
DOI: 10.1111/j.1750-3639.2011.00557

Giri S, Bader A
Improved preclinical safety assessment using micro-BAL devices: the potential impact on human discovery and drug attrition. Drug Discov Today 2011, 16(9-10): 382-397

Bellmann-Sickert K, Elling C, Nygaard Madsen A, Little PB, Lundgren K, Gerlach LO, Bergmann R, Holst B, Schwartz TW, Beck-Sickinger AG
Longacting lipidated analog of human pancreatic polypeptide is slowly released into circulation. J Med Chem 2011,54: 2658-67

Gräber M, Janczyk W, Sperl B, Elumalai N, Kozany C, Hausch F, Holak TA, Berg T

Selective targeting of disease-relevant protein binding domains by O-phosphorylated natural product derivatives. ACS Chem Biol 2011, 6: 008–1014

Geok Mei C, Jahr N, Singer D, Berger S
Hairpin conformation of an 11-mer peptide. Bioorganic & Medicinal Chemistry 2011, 19:3497-3501, DOI:10.1016/j.bmc.2011.04.020

Fischer S, Wiese C, Grosse Maestrup E,  Hiller A, Deuther-Conrad W, Scheunemann M, Schepmann D, Steinbach J,  Wünsch B, Brust P
Molecular imaging of σ receptors: synthesis and evaluation of the potent σ1  selective radioligand [18F]fluspidine. Eur J Nucl Med Mol Imaging 2011, 38: 540-551

Reitemeier S, Hänse M, Hahn A, Schmidt V, Steinbach-Sobiraj K, Krautwald-Junghanns ME, Einspanier A
Evaluating the reproductive status of the male budgerigar (Melopsittacus undulatus). General and Comparative Endocrinology 2011, 171(3): 350-8

Böhlig, L, Friedrich, M, Engeland, K

p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins. Nucleic Acids Research 2011, Jan, 39(2):440-53

Heretsch P, Büttner A, Tzagkaroulaki L, Zahn S, Kirchner B, Giannis A

Exo-Cyclopamine – a stable and potent inhibitor of hedgehog-signaling. Chem Commun 2011, 47: 7362-7364

Scholz M, Hey-Hawkins E
Carbaboranes as Pharmacophores: Properties, Synthesis, and Application Strategie. Chem Rev 2011, 111:7035

Xue J, Rai V,  Singer D, Chabierski S, Xie J, Reverdatto S, Burz SS, Schmidt AM,  Hoffmann R, Shekhtman A

Advanced glycation end product (AGE) recognition by the receptor for AGEs (RAGE). Structure 2011, 19 (5): 722-732

Halwachs S, Lakoma C, Schäfer I, Seibel P, Honscha W

The antiepileptic drugs phenobarbital and carbamazepine reduce transport of methotrexate in rat choroid plexus by down-regulation of the reduced folate carrier. Mol Pharmacol 2011 Oct, 80(4):621-9, Epub 2011 Jul 7

Schramedei K, Mörbt N, Pfeifer G, Läuter J, Rosolowski M, Tomm JM, von Bergen M, Horn F, Brocke-Heidrich K.
MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4. Oncogene 2011, 30(26): 2975-2985

Betz T, Koch D, Lu YB, Franze K, Käs J
Growth cones as soft and weak force generators. PNAS 2011, 108 (33): 13420-13425

Ueberschär, O, Wagner C, Stangner T, Gutsche C, Kremer F
The effective hydrodynamic radius of single DNA-grafted colloids as measured by fast Brownian motion analysis. Polymer 2011, 52: 1829-1836 , DOI:10.1016/j.polymer.2011.02.001

Scholz M, Engert A, Franklin J, Josting A, Diehl V, Hasenclever D, Loeffler M
Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL-experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis. Ann Oncol  2011, 22(3): 681-688

Windoffer R, Beil M, Magin TM, Leube RL
Cytoskeleton in Motion: The Case of Keratin Intermediate Filaments. J Cell Biol 2011, 194: 669-678

Bernt, M, Middendorf, M
A Method for Computing an Inventory of Metazoan Mitochondrial Gene Order Rearrangements. BMC Bioinformatics  2011, 12(9): S6

Tretbar S, Neuenfeldt A, Betat H, Mörl M
An inhibitory C-terminal Region dictates the Specificity of A-adding Enzymes. Proc Natl. Acad Sci USA 2011, 108 (52): 21040-21045

Berger F, Hensel A, Nieber K
Saffron extract and trans-crocetin inhibit glutamatergic synaptic transmission in rat cortical brain slices. Neuroscience 2011, Apr 28,180:238-47

Stamov D, Ngyuen K, Evans H, Pfohl T, Werner C, Pompe T

Intercalated heparin competes for the telopeptide binding site in collagen type I fibrils. Biomaterials 2011, 32:7444

Raz R, Rademann J
Fmoc-based synthesis of peptide thioesters for native chemical ligation employing a tert-butyl thiol linke. Org Lett, 2011, Apr 1;13(7):1606-9, Epub 2011 Feb 28

Kirsten, T, Groß, A, Hartung, M, Rahm, E
GOMMA: A Component-based Infrastructure for managing and analyzing Life Science Ontologies and their Evolution. Journal of Biomedical Semantics 2011, 2:6

Agte S, Junek S, Matthias S, Ulbricht E, Erdmann I, Wurm A, Schild D, Käs JA, Reichenbach A
Müller glial cell-provided cellular light guidance throush the vital guinea-pig retina. Biophys J 2011, 101: 2611-2619

Pänke, O, Weigel, W, Schmidt, S, Steude, A, Robitzki, AA
A cell-based impedance assay for monitoring transient receptor potential (TRP) ion channel activity. Biosensors and Bioelectronics 2011, 26 : 2376-2382

Reske AW, Rau A, Reske AP, Koziol M, Gottwald B, Alef M, Ionita JC, Spieth PM, Hepp P, Seiwerts M, Beda A, Born S, Scheuermann G, Amato MB, Wrigge H
Extrapolation in the analysis of lung aeration by computed tomography: a validation study. Crit Care 2011, Nov 23,15(6):R279, [Epub ahead of print]

Fuchs B, Süß R, Teuber K, Eibisch M, Schiller J
Application of TLC to the analysis of lipids. J Chromatogr A 2011, 1218: 2754-2774

Perseke M, Hetmank J, Bernt M, Stadler PF, Schlegel M, Bernhard D
The enigmatic mitochondrial genome of Rhabdopleura compacta (Pterobranchia) reveals insights into selection of an efficient tRNA system and supports monophyly of Ambulacraria. BMC Evolutionary Biology 2011, 11: 134

Muller-Hocker J, Horvath R, Schafer S, Hessel H, Muller-Felber W, Kuhr J, Copeland WC, Seibel P
Mitochondrial DANN depletion and fatal infantile hepatic failure due to mutations in the mitochondrial polymerase gamma (POLG) gene A combined morphological/enzyme histochemical and immunocytochemical/biochemical and molecular genetic study. J Cell Mol Med 2011, 15(2): 445-456

Simon JC, Boutin S, Tsuchida T, Koga R, Le Gallic JF, Frantz A, Outreman Y, Fukatsu T
Facultative symbiont infections affect aphid reproduction. PLoS One 2011, 6(7): e21831, Epub 2011 Jul 27

Jühling F, Pütz J, Bernt M, Donath A, Middendorf M, Florentz C, Stadler PF
Improved systematic tRNA gene annotation allows new insights into the evolution of mitochondrial tRNA structures and into the mechanisms of mitochondrial genome rearrangements. Nucleic Acids Res 2011, DOI:10.1093/nar/gkr1131

Sträter N, Marek S, Kuettner EB, Kloos M, Keim A, Brüser A, Kirchberger J, Schöneberg T
Molecular architecture and structural basis of allosteric regulation of eukaryotic phosphofructokinases. FASEB J 2011, 25: 89-98

Wilhelm C, Jakob T
From photons to biomass and biofuels: evaluation of possible light-dependent biotechnological processes based on comparative energy balances. Appl Microbiol Biot 2011, 92: 909-919

Kreisig T, Hoffmann R, Züchner T
Homogeneous Fluorescence-Based Immunoassay Detects Antigens Within 90 Seconds. Anal Chem, 2011, 83 (11): 4281-4287

letzte Änderung: 02.02.2017