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| Invited Talk, Thursday, 16:45 – 17:15 |
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| Cytoskeletal pattern formation:
Self organization of driven filaments
Andreas R. Bausch
Cellular Biophysics, Physik-Department
E27, Technische Universität München, James-Franck-Straße,
85747 Garching, Germany |
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| Contact:
| Website |
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Living cells rely on the self organization mechanisms of cytoskeleton to
adapt to their requirements. Especially in processes such as cell division,
intracellular transport or cellular motility the controlled self assembly
to well defined structures, which still allow a dynamic reorganization
on different time scales are of outstanding importance. Thereby, the intricate
interplay of cytoskeletal filaments, crosslinking proteins and molecular
motors a central role. One important and promising strategy to identify
the underlying governing principles is to quantify the physical process
in model systems mimicking the functional units of living cells.
Here I will present in vitro minimal model systems consisting of actin
filaments, crosslinking molecules and myosin-II filaments exhibiting collective
long range order and dynamics. I will discuss how a balance of local force
exertion, alignment interactions, crosslinking and hydrodynamics affect
the evolving dynamic structures. |
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