PoC - Physics of Cancer - Annual Symposium
The scientific program consists of invited and contributed talks as well as a poster session. The detailed schedule for the three days including all abstracts is available below. However, you may also download the program booklet as pdf file.

Talks:
All talk sessions take place in the seminar building ("Seminargebäude", 4th floor, seminar room 420) at the campus "Augustusplatz". Contributed talks are allocated 15 min (including discussion), whereas invited talks are allocated 20 min plus 10 min discussion.

Posters:
The session for poster presentation is on Friday, October 14, 2011 at 19:00 at the Institute of Experimental Physics I (1st floor, room 331 "Aula") at the campus "Johannisallee/Philipp-Rosenthal-Straße". During this session snacks and fingerfood will be provided for all.
Authors are asked to mount their posters already on October 13, 2011 between 09:00-12:00 or 19:00-20:30. In case you need help, please ask Bernd Kohlstrunk, (1st floor, room 302). The poster boards will be marked with the number according to the scientific program. Posters must fit within a rectangle 90 cm wide and 120 cm high (DIN A0), portrait format. The material necessary to mount the poster (pins or "Poster Strips") will be provided.

Download program booklet (PDF)


Thursday, October 13, 2011
 
14:00 – 14:15
Welcome
Matthias Schwarz (Vice Rector for Research and Young Academics at the University of Leipzig)
Session I: Biomechanics - From Polymers To Networks and Cells
14:15 – 14:45
Mechanobiology of the cytoskeleton and how it impacts on cell and tissue plasticity
Ueli Aebi (University of Basel, Switzerland)
14:45 – 15:00
Substrate-ligand friction modulates traction force
Tilo Pompe (University of Leipzig, Germany)
15:00 – 15:30
Tumor cells dissociation and peritumoral stromal rearrangement in squamous cell carcinoma of the uterine cervix
Lars-Christian Horn (University of Leipzig, Germany)
15:30 – 15:45
Collective cell migration on structured surfaces
Felix Segerer (LMU Munich, Germany)
15:45 – 16:15
Polar cortex mechanics and cell shape stability during cytokinesis
Ewa Paluch (Max Planck Institute of Molecular Cell Biology and Genetics, Germany)
16:15 – 16:45
Coffee break
16:45 – 17:15
Cytoskeletal pattern formation: Self organization of driven filaments
Andreas Bausch (Technical University Munich, Germany)
17:15 – 17:30
Microfluidic drops as tunable bio-environments
Christian Dammann (University of Göttingen, Germany)
17:30 – 18:00
Investigation of cellular mechanics by atomic force microscopy
Manfred Radmacher (University of Bremen, Germany)
18:00 – 18:30
Defined migration assays to study tumor cell migration
Ralf Kemkemer (Max Planck Institute for Intelligent Systems, Germany)

Friday, October 14, 2011
 
Session II: Cells At Work: Forces, Motion and Adhesion
09:00 – 09:30
Amplification of signaling pathways to actin polymerization and chemotaxis in breast tumor cells in vivo
John Condeelis (Albert Einstein College of Medicine of Yeshiva University, USA)
09:30 – 10:00
Intracellular pattern generation - mechanics meets biochemistry
Stefan Grill (Max Planck Institute of Molecular Cell Biology and Genetics, Germany)
10:00 – 10:15
Dynamics of growing cell populations
Anna-Kristina Marel (LMU Munich, Germany)
10:15 – 10:45
Physical limits in cell migration
Katarina Wolf (Radboud University Nijmegen, Netherlands)
10:45 – 11:15
Coffee break
11:15 – 11:45
The different phases of the force-velocity relation of motile cells
Martin Falcke (Max-Delbrück-Center for Molecular Medicine, Germany)
11:45 – 12:00
Physical determinants of vascular network remodeling during tumor growth
Heiko Rieger (Saarland University, Germany)
12:00 – 12:30
From waves to motion: Physics approaches to characterize and control individual and collective cell migration
Wolfgang Losert (University of Maryland, USA)
12:30 – 14:30
Lunch (organized for invited speakers only)
Session III: Physical Oncology I
14:30 – 15:00
Peptides Hormones: Tools and Drugs in Therapy and Diagnosis of Breast Cancer
Annette Beck-Sickinger (University of Leipzig, Germany)
15:00 – 15:30
Cytoskeletal filaments - new treatment targets in cancer?
Michael Beil (University of Ulm, Germany)
15:30 – 15:45
Mechanical cell phenotyping using microscopic imaging and computational modeling
Evgeny Gladilin (German Cancer Research Center, Germany)
15:45 – 16:15
Feeling for cell function with light
Jochen Guck (University of Cambridge, UK)
16:15 – 16:45
Coffee break
16:45 – 17:15
Tissue Simulations - Numerical methods for tissue growth
Jens Elgeti (Institut Curie, France)
17:15 – 17:30
Investigating the mechanics behind cellular compartmentalization and tumor spreading
Steve Pawlizak (University of Leipzig, Germany)
17:30 – 18:00
Role of fascin in invadopodia formation and turnover of focal adhesions
Danijela Vignjevic (Institut Curie, France)
Poster Session
19:00
The poster session takes place at the Institute for Experimental Physic I (Linnéstraße 5, 04103 Leipzig, 1st floor, room 331 "Aula"). During the session snacks and fingerfood will be provided for all.
01
Spatial oscillations during reorganization of Physarum polycephalum protoplasmic droplets
Marcus Hauser (Otto-von-Guericke University Magdeburg, Germany)
02
Nanomechanical profile of tumorigenic transformation in human and mouse breast biopsies
Marija Plodinec (University of Basel, Switzerland)
03
Online monitoring of cell adhesion in breast cancer cell lines treated with plant extracts
Nadja Engel-Lutz (University of Rostock, Germany)
04
Identification of SEC62 as a new migration stimulating oncogene in human lung cancer
Maximilian Linxweiler (Saarland University, Germany)
05
Modelling morphogenesis of glandular epithelia
Peter Buske (University of Leipzig, Germany)
06
Dynamics of Intermediate Filaments Confined in Microchannels
Bernd Nöding (Georg August University of Göttingen, Germany)
07
Malignancies in a Mouse Model Secondary to the Neutron Radiation Dosages Associated With Intensity-Modulated Radiation Therapy
Alex Herskovic (Northwestern University, USA)
08
Hydrodynamic deformation reveals two coupled timescales/modes of red blood cell relaxation
Thomas Franke (University Augsburg, Germany)
09
Geometry, topology, and out-of-equilibrium dynamics in epithelial morphogenesis
Benedetta Cerruti (Institute for Cancer Research and Treatment, Italy)
10
Cell encapsulation in alginate hollow spheres: A step towards true three dimensional cell culture
Bibhu Ranjan Sarangi (Institut Curie, Paris)
11
Tumor interstitial fluid pressure: a biophysical barrier hampering the uptake of macromolecular therapeutics
Matthias Hofmann (Goethe University Frankfurt, Germany)
12
Local membrane mechanical probing of neoplastic and non-neoplastic human cells
Dan Cojoc (University of Trieste, Italy)
13
Non-invasive investigation of biomechanical properties in mice tumor xenografts via scanning acoustic microscopy
Ralph Pflanzer (Goethe University Frankfurt, Germany)
14
Some observations on the growth of tumors in hydrogel environments
Kristen Mills (Max Planck Institute for Intelligent Systems, Germany)
15
Influence of calcium signaling on biomechanics of single suspended cells in the Optical Stretcher
Markus Gyger (University of Leipzig, Germany)
16
Blood vessel network remodeling during tumor growth
Michael Welter (Saarland University, Germany)
17
The Rho-GTPase-activating protein myosin IXb regulates cell migration and cell-cell communication
Yan Xu & Zhijun Liu (Westfalian Wilhelms University Münster, Germany)
18
Formation of regular actin networks as general feature of entropic forces
Florian Huber & Dan Strehle (University of Leipzig, Germany)
19
Biomechanical Features Of The Cell Nucleus During Optical Stretching
Enrico Warmt (University of Leipzig, Germany)
20
The Automated Microfluidic Optical Stretcher
Roland Stange (University of Leipzig, Germany)
21
Biomechanical analysis of primary breast cancer cells
Franziska Wetzel (University of Leipzig, Germany)
22
On the Interpretation of Optically Induced Cell Deformations - Part I: Temperature Dependence
Tobias Kießling & Anatol Fritsch (University of Leipzig, Germany)
23
Influence of cell cycle stage on the optical deformability of cells
Susanne Rönicke (University of Leipzig, Germany)
24
Impact of jamming on collective cell dynamics
Kenechukwu David Nnetu (University of Leipzig, Germany)
25
Insight into the cell-beam interaction in the Optical Stretcher
Steffen Grosser (University of Leipzig, Germany)
26
Manipulation of cellular mechanics
Anna Pietuch (Georg August University of Göttingen, Germany)
27
Keratin-mediated repression of cell migration
Kristin Seltmann (University of Leipzig, Germany)

Saturday, October 15, 2011
 
Session IV: Physical Oncology II
09:00 – 09:30
Cancer Cell Motility in 3D
Denis Wirtz (Johns Hopkins University, USA)
09:30 – 09:45
Development of a novel biosensoric screening system for direct chemosensitivity testing on tumor biopsy material
Sarah Pönick (Center for Biotechnology and Biomedicine, Germany)
09:45 – 10:15
Exploring the impact of cell mechanics on cancer progression with the Microfluidic Optical Stretcher
Mareike Zink (University of Leipzig, Germany)
10:15 – 10:30
How changes in cell mechanical properties induce cancerous behavior
Parag Katira (The University of Texas at Austin, USA)
10:30 – 11:00
Cancer cells regulate biomechanical properties of human microvascular endothelial cells
Claudia Mierke (University of Leipzig, Germany)
11:00 – 11:30
Coffee break
11:30 – 12:00
Targeting the cytoskeletal physics of circulating breast tumor cells to reduce metastasis
Stuart Martin (University of Maryland, USA)
12:00 – 12:15
Fingering instabilities and cellular pathways in epithelial tissues and their connection to tumor growth
Thomas Risler (Institute Curie, Paris, France)
12:15 – 12:45
Molecular Mechanotransduction: how forces trigger cytoskeletal dynamics
Allen Ehrlicher (Harvard University, USA)
13:00
Prospective end

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