Bilal Sheikh
Dissecting neurovascular function in health and disease
Brain Dynamics Graduate School is happy to announce a new talk within our Seminar Series:
- Dr. Bilal Sheikh
Helmholtz Institute for Metabolic, Obesity and Vascular Research (Hl-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig
"Dissecting neurovascular function in health and disease"
19th January 2024, 12:00
Paul Flechsig Institute - Center of Neuropathology and Brain Research, Room 3093, Liebigstraße 19 (Haus C), 04103 Leipzig
Abstract:
Neurovascular defects underlie and promote all major neural pathologies such as Alzheimer's disease. Our work focuses on identifying metabolic factors that trigger neurovascular breakdown and subsequent neural dysfunction. During my talk, I will share examples of our work - where we have identified metabolites that trigger neurovascular breakdown in developmental syndromes, metabolic disease, and neurodegeneration. A better understanding of how neural vessels maintain brain homeostasis, how their dysregulation promotes disease, how they communicate with other neural cells, and the ultimate therapeutic targeting of neurovascular health will be critical for targeting a range of neural disorders such as dementia that are underpinned by vascular defects.