Profile

Professional career

• since 12/2007
  W3 Professor of Immuno-Oncology at the University of Leipzig, Director of the Institute of Clinical Immunology at Leipzig University Hospital, and Head of the Fraunhofer Institute for Cell Therapy and Immunology (IZI)
• 01/2012 - 08/2023
  W3 Professor and Director of the Institute for Cell Therapeutics, leading the "GMP Development Unit" and the "Cellular Therapy Centre" at Hannover Medical School
• 01/2008 - 12/2010
  Acting Head of the Emergency Laboratory for Hematology and Coagulation, Pediatric Hematology, Oncology, and Hemostasis, University Hospital Frankfurt am Main (UKF)
• 01/2000 - 12/2012
  Head of the Laboratory for Stem Cell Transplantation and Immunotherapy, Pediatric Hematology, Oncology, and Hemostasis, University Hospital Frankfurt am Main (UKF)
• 01/1996 - 12/1999
  Senior Scientist, Establishment of a Stem Cell Transplantation Laboratory, Pediatric Hematology and Oncology, University Hospital Frankfurt am Main (UKF)
• 01/1995 - 12/1996
  Postdoctoral Fellow at MD Anderson Cancer Center, Molecular Cell Therapy, Houston, USA
• 01/1987 - 12/1995
  Scientific Associate, Pharmacokinetics Laboratory, Pediatric Hematology and Oncology, Johann Wolfgang Goethe University Frankfurt am Main

Education

• since 01/1213
  Qualified Person (QP according to §14 and §20c of the German Medicines Act (AMG))
• since 07/2008
  Habilitation, Venia Legendi in Experimental Medicine, Johann Wolfgang Goethe University (JWGU) Frankfurt am Main
• since 08/2006
  Second State Examination in Human Medicine, JWGU Frankfurt
• since 09/1995
  Ph.D. in Natural Sciences with a focus on Pharmacology, JWGU Frankfurt
• since 07/1987
  Diploma in Biology (Microbiology, Pharmacology, Biochemistry), JWGU Frankfurt

Panel Memberships

• since 01/2017
  Spokesperson for several EU consortia
• since 01/2021
  Spokesperson of the BMBF-funded Future Cluster "SaxoCell"
• since 01/2017
  
• since 01/2017
  Editor at Frontiers in Immunology
• since 01/2015
  Co-Editor at Frontiers in Immunology
• since 01/2017
  Reviewer for numerous scientific journals (e.g., New England Journal of Medicine and Nature Medicine) and various national and international foundations
• since 01/2017
  Membership in numerous scientific professional organizations, including DGfI, DG-GT, DGHO, EBMT, ESMO, GPOH, ISCT
• since 01/2023
  Member of the Saxon Academy of Sciences in Leipzig

• SaxoCell® - Präzisionstherapie-Cluster für „Lebende Arzneimittel“

  Köhl, Ulrike

  Duration: 10/2021 – 09/2024

  Funded by: BMBF Bundesministerium für Bildung und Forschung

  Involved organisational units of Leipzig University: Institut für Klinische Immunologie
  show details
• Immune Safety Avatar: nonclinical mimicking of the immune system effects of immunomodulatory therapies (ImSAVAR)

  Köhl, Ulrike

  Duration: 01/2019 – 12/2025

  Funded by: EU Europäischer Sozialfonds (ESF)

  Involved organisational units of Leipzig University: Institut für Klinische Immunologie
  show details
• Chimeric antigen receptor (CAR) effector cells in immuno-oncology: Development of a functional assay to quantify the effectiveness.

  Köhl, Ulrike

  Duration: 02/2019 – 12/2020

  Funded by: Vereine/Gesellschaft

  Involved organisational units of Leipzig University: Institut für Klinische Immunologie
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• „Central European Advanced Therapy and Immunotherapy Centre“ (CREATIC)

  Köhl, Ulrike

  Duration: 06/2023 – ongoing

  Funded by: EU Europäische Union

  Involved organisational units of Leipzig University: Institut für Klinische Immunologie
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more projects

• von Auw, N.; Serfling, R.; Kitte, R.; Hilger, N.; Zhang, C.; Gebhardt, C.; Duenkel, A.; Franz, P.; Köhl, U.; Fricke, S.; Tretbar, U. S.

  Comparison of two lab-scale protocols for enhanced mRNA-based CAR-T cell generation and functionality

  Scientific reports. 2023.

  DOI: 10.1038/s41598-023-45197-x
  show details
• Schmidt, J. R.; Haupt, J.; Riemschneider, S.; Kämpf, C.; Löffler, D.; Blumert, C.; Reiche, K.; Köhl, U.; Kalkhof, S.; Lehmann, J.

  Transcriptomic signatures reveal a shift towards an anti-inflammatory gene expression profile but also the induction of type I and type II interferon signaling networks through aryl hydrocarbon receptor activation in murine macrophages

  Frontiers in immunology. 2023.

  DOI: 10.3389/fimmu.2023.1156493
  show details
• Schimmelpfennig, C.; Rade, M.; Fuessel, S. et al.

  Characterization and evaluation of gene fusions as a measure of genetic instability and disease prognosis in prostate cancer

  BMC cancer. 2023. 23 (1).

  DOI: 10.1186/s12885-023-11019-6
  show details
• Feigl, F. F.; Stahringer, A.; Peindl, M.; Dandekar, G.; Köhl, U.; Fricke, S.; Schmiedel, D.

  Efficient Redirection of NK Cells by Genetic Modification with Chemokine Receptors CCR4 and CCR2B

  International journal of molecular sciences. 2023. 24 (4).

  DOI: 10.3390/ijms24043129
  show details
• Wagner, D. L.; Köhl, U.; Chmielewski, M.; Scheid , C.; Stripecke, R.

  Review: Sustainable Clinical Development of CAR-T Cells - Switching From Viral Transduction Towards CRISPR-Cas Gene Editing

  Frontiers in immunology. 2022.

  DOI: 10.3389/fimmu.2022.865424
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more publications

• Gastprofessur: Lecture Award und Visiting Professor Newcastle University

  Köhl, Ulrike (Institut für Klinische Immunologie)

  awarded in 2015 by Newcastle University, UK.
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• Andere herausragende Auszeichnungen: Gutermuth-Preis: Entwicklung von Immuntherapien zur Leukämiebehandlung.

  Köhl, Ulrike (Institut für Klinische Immunologie)

  awarded in 2005.
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• Andere herausragende Auszeichnungen: Wissenschaftspreis der GPOH „Israeli-German Bi-National Conference“

  Köhl, Ulrike (Institut für Klinische Immunologie)

  awarded in 1999.
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more awards

• Nationaler Kongress

  Leipzig Immune Oncology Conference (LION)

  Institut für Klinische Immunologie

  Event Organiser: Köhl, Ulrike

  11/11/2024 – 12/11/2024
  show details

more events

• Human Medicine, Immuno-Oncology, Lecture

• Human Medicine, Molecular Medicine, Lecture

• Molecular Science, GMP Training for Cell and Gene Therapies