Profile

Professional career

• since 05/2025
  Appointed member to the medical faculty, Leipzig University
• since 12/2024
  "Privatdozent", permission to teach (venia legendi) at the medical faculty, Leipzig University
• since 11/2024
  Habilitation (academic teaching qualification) in internal medicine and respiratory medicine
• since 05/2023
  Chest physician, board certified
• since 01/2018
  Internal medicine specialist, board certified
• since 11/2017
  Doctorate degree in medicine (Dr. med.), Leipzig University

Panel Memberships

• since 07/2024
  Member of the European Respiratory Society (ERS) College of Experts / Fellowships and Awards programme
• since 04/2024
  Participation in the S3 guideline: Prevention, diagnosis, treatment and follow-up of lung cancer - Living Guideline, AWMF register number: 020-007OL, mandated by the German Respiratory Society (DGP)
• since 07/2023
  Participation in the Taskforce on the management of positive findings in low-dose CT screening for lung cancer – a joint ERS and ESR/ESTI Clinical Practice Guideline in collaboration with ESTRO, ESTS and ELF
• since 06/2023
  Participation in the S3 guideline on “Nutrition in oncology”, guideline program oncology, AWMF register number: 073-006OL, mandated by the German Respiratory Society (DGP)
• since 03/2022
  Participation in the S3 guideline “Exercise therapy in oncological diseases”, guideline program oncology, AWMF register number: 032-058OL, mandated by the German Respiratory Society (DGP)
• 09/2020 - 08/2024
  Member of the Long-Range Planning Committee der Assembly 11 Thoracic Oncology der European Respiratory Society (ERS)
• since 11/2020
  Participation in the ERS/ESTS Clinical Practice Guideline Task Force (TF-2020-07) on Fitness for Tumour-specific Treatments of Lung Cancer (Taskforce 2020-07)
• since 11/2019
  Speaker for the thoracic oncology assembly, Central German Society for Pneumology and Thoracic Surgery e.V. (MDGP)
• since 04/2018
  Member of the German Society of Internal Medicine
• since 03/2016
  Member of the German Respiratory Society
• since 01/2016
  Member of the European Lung Foundation, Lung Cancer Reviewing Panel
• since 09/2014
  Member of the Central German Society for Pneumology and Thoracic Surgery e.V. (MDGP)
• since 09/2012
  Member of the European Respiratory Society (ERS)

• Translational lung cancer research
• Molecular mechanisms in the development of cachexia in patients with chronic lung disease or lung cancer
• Multidisciplinary molecular imaging techniques in lung cancer
• Pulmonary hypertension

• Clinical decision support for predicting cachexia in cancer patients using hybrid PET/CT imaging

  Sabri, Osama

  Duration: 01/2021 – ongoing

  Funded by: EU Europäische Union

  Involved organisational units of Leipzig University: Klinik und Poliklinik für Nuklearmedizin
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• Prospective analysis of adipokines’ influence on the development of cachexia in lung cancer patients

  Frille, Armin

  Duration: 01/2019 – 12/2022

  Funded by: Haushaltsmittel (TG51, Overhead); Vereine/Gesellschaft; BMBF Bundesministerium für Bildung und Forschung

  Involved organisational units of Leipzig University: Innere Medizin mit Schwerpunkt Pneumologie; Integriertes Forschungs- und Behandlungszentrum (IFB) AdipositasErkrankungen
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• Analysis of interactions between brown adipose tissue and lung cancer cells in the context of resistance to chemotherapy and cancer cachexia

  Frille, Armin

  Duration: 10/2017 – 12/2022

  Funded by: BMBF Bundesministerium für Bildung und Forschung; Haushaltsmittel (TG51, Overhead)

  Involved organisational units of Leipzig University: Innere Medizin mit Schwerpunkt Pneumologie; Integriertes Forschungs- und Behandlungszentrum (IFB) AdipositasErkrankungen
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• Mechanisms of activation of brown adipose tissue (BAT)in patients with pulmonary cachexia

  Hesse, Swen

  Duration: 01/2017 – ongoing

  Funded by: BMBF Bundesministerium für Bildung und Forschung

  Involved organisational units of Leipzig University: Klinik und Poliklinik für Nuklearmedizin
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• Identification of prognostic and predictive morpho-molecular biomarkers in stage I non-small cell lung cancer (NSCLC)

  von Laffert, Maximilian

  Duration: 02/2023 – ongoing

  Involved organisational units of Leipzig University: Innere Medizin mit Schwerpunkt Pneumologie; Institut für Pathologie; Klinik und Poliklinik für Diagnostische und Interventionelle Radiologie; Klinik und Poliklinik für Nuklearmedizin
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more projects

• Kuhn, H.; Frille, A.; Petersen, M. A.; Oberhuber-Kurth, J.; Hofmann, L.; Gläser, A.; Taubenheim, S.; Klagges, S.; Krämer, S.; Broschewitz, J.; von Laffert, M.; Wirtz, H.

  IGFBP3 inhibits tumor growth and invasion of lung cancer cells and is associated with improved survival in lung cancer patients

  Translational Oncology. 2023. p. 101566.
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• Hardavella, G.; Frille, A.; Chalela, R.; Sreter, K. B.; Petersen, R. H.; Novoa, N.; de Koning, H. J.

  How will lung cancer screening and lung nodule management change the diagnostic and surgical lung cancer landscape?

  European Respiratory Review. 2024. 33 (172).

  DOI: 10.1183/16000617.0232-2023
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• Ferrara, D.; Abenavoli, E. M.; Beyer, T. et al.

  Detection of cancer-associated cachexia in lung cancer patients using whole-body [18F]FDG-PET/CT imaging: A multi-centre study

  Journal of Cachexia Sarcopenia and Muscle. 2024.

  DOI: 10.1002/jcsm.13571
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• Frille, A.; Boeschen, M.; Wirtz, H.; Stiller, M.; Bläker, H.; von Laffert, M.

  TP53 co-mutations in advanced lung adenocarcinoma: comparative bioinformatic analyses suggest ambivalent character on overall survival alongside KRAS, STK11 and KEAP1 mutations (vol 14, 1357583, 2024)

  Frontiers in Oncology. 2024.

  DOI: 10.3389/fonc.2024.1473239
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• Frille, A.; Arends, J.; Abenavoli, E. M. et al.

  "Metabolic fingerprints" of cachexia in lung cancer patients

  European Journal of Nuclear Medicine and Molecular Imaging. 2024. 51 (7). pp. 2067–2069.

  DOI: 10.1007/s00259-024-06689-8
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more publications

• Andere Stipendien/Forschungspreise: Graduierten-Stipendium 2023 der Novartis-Stiftung für therapeutische Forschung

  Frille, Armin (Innere Medizin mit Schwerpunkt Pneumologie)

  awarded in 2023 by Novartis-Stiftung für therapeutische Forschung.
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• Publikationspreis: Preis für das beste wissenschaftliche Poster

  Frille, Armin (Innere Medizin mit Schwerpunkt Pneumologie)

  awarded in 2019 by 22. Herbsttagung durch die Mitteldeutsche Gesellschaft für Pneumologie und Thoraxchirurgie (MDGP) .
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• Publikationspreis: Preis für das beste wissenschaftliche Poster

  Frille, Armin (Innere Medizin mit Schwerpunkt Pneumologie)

  awarded in 2019 by 57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin (DGN).
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• Andere Stipendien/Forschungspreise: Projektförderung durch das Nachwuchsförder-Programm

  Frille, Armin (Innere Medizin mit Schwerpunkt Pneumologie)

  awarded in 2019 by Medizinische Fakultät der Universität Leipzig.
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• Andere Stipendien/Forschungspreise: Postdoktorales Forschungsstipendium (MetaRot-Programm)

  Frille, Armin (Innere Medizin mit Schwerpunkt Pneumologie)

  awarded in 2018 by Integriertes Forschungs- und Behandlungszentrums (IFB) AdipositasErkrankungen, Universitätsmedizin Leipzig.
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more awards

Medical Studies

• Lecture in respiratory medicine: lung cancer (4th year)
• Seminar about respiratory medicine for students during their elective period (6th year, 'PJ')
• Review course in respiratory medicine, elective period (6th year)
• Bedside teaching in respiratory medicine (4th year)
• Clinical examination course in internal medicine (3rd year)
• Seminar: introduction to clinical medicine (1st - 2nd year)
• Seminar on lung cancer for the 'Master of Science Clinical Research and Translational Medicine' course, Clinical trial centre (ZKS) Leipzig, University of Leipzig

Dentistry studies

• Lecture in respiratory medicine

Medical informatics studies

• Lecture and seminar in internal medicine and respiratory medicine

Oncology training for nursing staff

• Lecture on lung cancer